SGD Paper 
Page Contents:
Passmore LA (2004) The anaphase-promoting complex (APC): the sum of its parts? Biochem Soc Trans 32(Pt 5):724-7
Abstract: The APC (anaphase-promoting complex) is a multisubunit E3 ubiquitin ligase that targets cell-cycle-related proteins for degradation by the 26 S proteasome. The APC contains at least 13 subunits and is regulated by the binding of co-activator proteins and by phosphorylation. It is not known why the APC contains 13 subunits when many other ubiquitin ligases are small single-subunit enzymes. In the present study, the structures and functions of individual APC subunits are discussed. By dissecting the roles of its parts, we hope to gain insight into the mechanism of the intact APC.
| Status: Published | Type: Journal Article | Research Support, Non-U.S. Gov't | Review | PubMed ID: 15493998 |
Topics addressed in this paper
Number of different genes curated to this paper: 16
Jump to Summary Chart for:
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| AMA1 | APC1 | APC11 | APC2 | APC4 | APC5 | APC9 | CDC16 | CDC20 | CDC23 | |
| Reviews |  | | | | | | | | | |
Page Contents:
