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Lee KM and O'Connell MJ  (2006) A new SUMO ligase in the DNA damage response. DNA Repair (Amst) 5(1):138-41

Abstract: SUMO is a small ubiquitin-like protein that is attached to target proteins, altering their localization and function. The condensin and cohesin-related Smc5/6 complex has been linked to DNA repair and checkpoint responses, but details of its molecular function have remained obscure. Recent reports show one subunit of the complex is a SUMO ligase, providing another link between protein sumoylation and DNA damage responses.

Status: Published Type: Journal Article | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | Review PubMed ID: 16198156

Topics addressed in this paper

Number of different genes curated to this paper: 26

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Topics Genes linked to topics (#1 - 10 )
IRR1 MCD1 MLP1 MLP2 MMS2 MMS21 NFI1 NSE1 NSE3 NSE4
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Topics Genes linked to topics (#11 - 20 )
POL30 RAD18 RAD5 RAD51 RAD52 RAD6 SMC1 SMC2 SMC5 SMC6
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Topics Genes linked to topics (#21 - 26 )
SRS2 TOP1 TOP2 UBC13 UBC9 ULP1
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