Brahemi G, et al. (2010) Homology Modelling of Human E1 Ubiquitin Activating Enzyme. Lett Drug Des Discov 7(1):57-62
Abstract: Human E1 is a key player in protein ubiquitination, however the E1 structure is not available. In this paper, we describe the derivation of a human E1 structure using molecular modelling based on the crystal structure of S. cerevisiae E1 and M. Musculus E1. Key interactions between our E1 model and ubiquitin are also discussed.
|Status: Published||Type: Journal Article||PubMed ID: 20396627|
Topics addressed in this paper
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|Topics||Genes linked to topics|
|Non-Fungal Related Genes/Proteins|
|Protein/Nucleic Acid Structure|