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Yokogawa T, et al.  (2009) Preparation of an ochre suppressor tRNA recognizing exclusively UAA codon by using the molecular surgery technique. Nucleic Acids Symp Ser (Oxf)(53):295-6

Abstract: In order to create an ochre suppressor tRNA which exclusively recognizes UAA codon, we replaced the G34 at the first position of yeast tRNA(Tyr)[GPsiA] anticodon with pseudouridine34 (Psi34) by using the molecular surgery technique. This tRNA(Tyr)[PsiPsiA] recognized only the UAA codon as expectedly, but tRNA(Tyr)[UPsiA] made as a control also behaved similarly. This result may suggest that U34 must be somehow modified to facilitate the wobble-pairing to G at the third position of codon.

Status: Published Type: Journal Article PubMed ID: 19749377

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SUP11 SUP2 SUP3 SUP4 SUP5 SUP6 SUP7 SUP8 tY(GUA)Q TYS1
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