Yokogawa T, et al. (2009) Preparation of an ochre suppressor tRNA recognizing exclusively UAA codon by using the molecular surgery technique. Nucleic Acids Symp Ser (Oxf)(53):295-6
Abstract: In order to create an ochre suppressor tRNA which exclusively recognizes UAA codon, we replaced the G34 at the first position of yeast tRNA(Tyr)[GPsiA] anticodon with pseudouridine34 (Psi34) by using the molecular surgery technique. This tRNA(Tyr)[PsiPsiA] recognized only the UAA codon as expectedly, but tRNA(Tyr)[UPsiA] made as a control also behaved similarly. This result may suggest that U34 must be somehow modified to facilitate the wobble-pairing to G at the third position of codon.
|Status: Published||Type: Journal Article||PubMed ID: 19749377|
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