Krebs A and Tora L (2009) Keys to open chromatin for transcription activation: FACT and Asf1. Mol Cell 34(4):397-9
Abstract: In this issue of Molecular Cell, Takahata et al. (2009) dissect the mechanisms preceding transcription initiation, revealing a wave of nucleosome eviction, which spreads from distant cis-regulatory elements to promoters and which requires the activity of histone chaperones, FACT and Asf1.
|Status: Published||Type: Comment | Journal Article||PubMed ID: 19481517|
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