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Rexach M  (2009) Piecing together nuclear pore complex assembly during interphase. J Cell Biol 185(3):377-9

Abstract: All nucleocytoplasmic traffic of macromolecules occurs through nuclear pore complexes (NPCs), which function as stents in the nuclear envelope to keep nuclear pores open but gated. Three studies in this issue (Flemming, D., P. Sarges, P. Stelter, A. Hellwig, B. Bottcher, and E. Hurt. 2009. J. Cell Biol. 185:387-395; Makio, T., L.H. Stanton, C.-C. Lin, D.S. Goldfarb, K. Weis, and R.W. Wozniak. 2009. J. Cell Biol. 185:459-491; Onishchenko, E., L.H. Stanton, A.S. Madrid, T. Kieselbach, and K. Weis. 2009. J. Cell Biol. 185:475-491) further our understanding of the NPC assembly process by reporting what happens when the supply lines of key proteins that provide a foundation for building these marvelous supramolecular structures are disrupted.

Status: Published Type: Comment | Journal Article PubMed ID: 19414605

Topics addressed in this paper

Number of different genes curated to this paper: 13

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Topics Genes linked to topics (#1 - 10 )
ASM4 NDC1 NIC96 NUP157 NUP170 NUP188 NUP53 NUP82 NUP84 POM152
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Topics Genes linked to topics (#11 - 13 )
POM34 RTN1 YOP1
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