Biddick R and Young ET (2009) The disorderly study of ordered recruitment. Yeast 26(4):205-20
Abstract: Activated transcription in eukaryotes requires the aid of numerous co-factors to overcome the physical barriers chromatin poses to activation, bridge the gap between activators and polymerase, and ensure appropriate regulation. S. cerevisiae has long been a model organism for studying the role of co-activators in the steps leading up to gene activation. Detailed studies on the recruitment of these co-activators have been carried out for more than a dozen promoters. Taking a step back to survey these results, however, suggests that there are few generalizations that could be used to guide future studies of uncharacterized promoters.
Type: Journal Article
PubMed ID: 19330770
Topics addressed in this paper
Number of different genes curated to this paper: 129
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