Gong J and Siede W (2009) SBF transcription factor complex positively regulates UV mutagenesis in Saccharomyces cerevisiae. Biochem Biophys Res Commun 379(4):1009-14
Abstract: The collection of gene deletion mutants of Saccharomyces cerevisiae was used to screen for novel genes required for UV-induced mutagenesis. We found the SBF transcription factor (Swi4/Swi6 protein complex) to be required for wild-type levels of UV mutability in forward and reverse mutation assay. Expression of translesion polymerase zeta component Rev7 was identified as a target of SBF-dependent regulation.
|Status: Published||Type: Journal Article||PubMed ID: 19150335|
Topics addressed in this paper
Number of different genes curated to this paper: 8
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