SGD Paper 
Page Contents:
Bianchi A and Shore D (2008) How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex. Mol Cell 31(2):153-65
Abstract: The telomerase enzyme, which synthesizes telomeric DNA repeats, is regulated in cis at individual chromosome ends by the telomeric protein/DNA complex in a manner dependent on telomere repeat-array length. A dynamic interplay between telomerase-inhibiting factors bound at duplex DNA repeats and telomerase-promoting ones bound at single-stranded terminal DNA overhangs appears to modulate telomerase activity and to be directly related to the transient deprotection of telomeres. We discuss recent advances on the mechanism of telomerase regulation at chromosome ends in both yeast and mammalian systems.
| Status: Published | Type: Journal Article | Research Support, Non-U.S. Gov't | PubMed ID: 18657499 |
Topics addressed in this paper
Number of different genes curated to this paper: 17
Jump to Summary Chart for:
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CDC13 | EST1 | EST2 | EST3 | MEC1 | MRE11 | RAP1 | RFA2 | RIF1 | RIF2 | |
| Alias |  | |||||||||
| Reviews | | | | | | | | | | |
Page Contents:
