VITOLS E, et al. (1970) Ribonucleotide reductase from Saccharomyces cerevisiae. Biochem Biophys Res Commun 41(1):71-7
Abstract: Partially purified ribonucleotide reductase from Saccharomyces cerevisiae was unstable in solution; however, enzyme activity could be maintained by quick-freezing and storage at low temperatures. The reduction of CDP was stimulated by ATP/Mg++, and maximal activity was obtained with E. coli thioredoxin as a reductant, but not with dithioerythritol. Enzyme activity was inhibited by dATP, hydroxyurea, and moderately high salt concentrations; addition of 5′-deoxyadenosylcobalamin or of iron salts was without effect. Gel filtration of the yeast extract yielded a fraction highly inhibitory to enzyme activity.
|Status: Published||Type: Journal Article||PubMed ID: 5459124|
Topics addressed in this paper
Number of different genes curated to this paper: 4
- To go to the Locus page for a gene, click on the gene name.