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Haag JR and Pikaard CS (2007) RNA polymerase I: a multifunctional molecular machine. Cell 131(7):1224-5
Abstract: In this issue, Kuhn et al. (2007) report the complete structure of the 14-subunit yeast RNA polymerase (Pol) I enzyme at 12 A resolution using cryo-electron microscopy (cryo-EM). Their study reveals that three subunits of Pol I perform functions in transcription elongation that are outsourced to the transcription factors TFIIF and TFIIS in the analogous Pol II transcription system.
| Status: Published | Type: Comment | Journal Article | PubMed ID: 18160031 |
Topics addressed in this paper
Number of different genes curated to this paper: 14
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| RPA12 | RPA135 | RPA14 | RPA190 | RPA34 | RPA43 | RPA49 | RPB10 | RPB5 | RPB8 | |
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