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Ball SG, et al.  (1984) Genetic Control of L-a and L-(Bc) Dsrna Copy Number in Killer Systems of SACCHAROMYCES CEREVISIAE. Genetics 107(2):199-217

Abstract: M dsRNA in yeast encodes a toxin precursor and immunity protein, whereas L-A dsRNA encodes the 81,000-dalton major protein of the intracellular particles in which both L-A and M are found. L-(BC) dsRNA(s) are found in particles with different coat proteins. We find that M dsRNA lowers the copy number of L-A, but not L-(BC). The SKI gene products lower the copy number of L-(BC), L-A, M(1) and M(2). This is the first known interaction of L-(BC) with any element of the killer systems. The MAK3, MAK10 and PET18 gene products are necessary for L-A maintenance and replication, but mutations in these genes do not affect L-(BC) copy number. Mutations in MAK1, MAK4, MAK7, MAK17 and MAK24 do not detectably affect copy number of L-(BC) or L-A.

Status: Published Type: Journal Article PubMed ID: 17246214

Topics addressed in this paper

Number of different genes curated to this paper: 13

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Topics Genes linked to topics (#1 - 10 )
CSL4 MAK10 MAK24 MAK3 MAK4 MKT1 PET18 RPL8A SKI2 SKI3
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Other Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Strains/Constructs blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#11 - 13 )
SKI7 SKI8 TOP1
Additional Literature blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball
Other Features blue ball blue ball blue ball
Strains/Constructs blue ball blue ball blue ball

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