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Fujita K, et al.  (2006) The genome-wide screening of yeast deletion mutants to identify the genes required for tolerance to ethanol and other alcohols. FEMS Yeast Res 6(5):744-50

Abstract: A set of homozygous diploid deletion mutants of the yeast Saccharomyces cerevisiae was screened for the genes required for tolerance to aliphatic alcohols. The screen identified 137, 122 and 48 deletion mutants sensitive to ethanol, 1-propanol and 1-pentanol, respectively. A number of the genes required for ethanol tolerance were those also required for tolerance to other alcohols. Numerous mutants with defective genes encoding for vacuolar H+ -ATPase (V-ATPase) were cosensitive to these alcohols. A global screening approach of yeast deletion library mutants was useful in elucidating the mechanisms of alcohol tolerance based on different lipophilicities.

Status: Published Type: Journal Article PubMed ID: 16879425

Topics addressed in this paper

Number of different genes curated to this paper: 26

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Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
ARD1 BCK1 BRO1 DHH1 ELM1 GIM3 GIM4 GIM5 MEH1 NAT1
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Topics Genes linked to topics (#11 - 20 )
PAC10 SLT2 SNF1 SSD1 STP22 VMA1 VMA13 VMA16 VMA2 VMA3
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Topics Genes linked to topics (#21 - 26 )
VMA4 VMA6 VMA8 VPH2 VPS28 YKE2
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