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Dimster-Denk D, et al.  (1999) Comprehensive evaluation of isoprenoid biosynthesis regulation in Saccharomyces cerevisiae utilizing the Genome Reporter Matrix. J Lipid Res 40(5):850-60

Abstract: Gene expression profiling is rapidly becoming a mainstay of functional genomic studies. However, there have been relatively few studies of how the data from expression profiles integrate with more classic approaches to examine gene expression. This study used gene expression profiling of a portion of the genome of Saccharomyces cerevisiae to explore the impact of blocks in the isoprenoid biosynthetic pathway on the expression of genes and the regulation of this pathway. Approximately 50% of the genes whose expression was altered by blocks in isoprenoid biosynthesis were genes previously known to participate in the pathway. In contrast to this simple correspondence, the regulatory patterns revealed by different blocks, and in particular by antifungal azoles, was complex in a manner not anticipated by earlier studies.

Status: Published Type: Journal Article PubMed ID: 10224154

Topics addressed in this paper

Number of different genes curated to this paper: 49

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Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
ARE1 ARE2 BEM1 BET2 BET4 BTS1 CAT5 CDC43 COQ1 COQ2
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Genomic expression study blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#11 - 20 )
COQ3 COQ6 COX10 ERG1 ERG10 ERG11 ERG12 ERG13 ERG2 ERG20
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Topics Genes linked to topics (#21 - 30 )
ERG24 ERG3 ERG4 ERG5 ERG6 ERG7 ERG8 ERG9 FAR1 FAR3
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Genomic expression study blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Jump to Summary Chart for:
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  • displays other papers with information about that topic for that gene.
  • displays other papers in SGD that are associated with that topic.
    The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
  • To go to the Locus page for a gene, click on the gene name.

Topics Genes linked to topics (#31 - 40 )
FUS1 HEM14 HMG1 HMG2 IDI1 KAR4 MFA1 MFA2 MOD5 MVD1
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Topics Genes linked to topics (#41 - 49 )
RAM1 RAM2 RAS1 RAS2 RCE1 STE14 STE18 STE2 STE24
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Genomic expression study blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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