Douville J, et al. (2006) The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure. Genetics 172(2):1369-72
Abstract: We show that mutants lacking either the phosphatase activator Rrd1 or the phosphatase Pph3 are resistant to rapamycin and that double mutants exhibit a synergistic response. This phenotype could be related to an inability of the mutants to degrade RNA polymerase II, leading to transcription of critical genes that sustain growth.
|Status: Published||Type: Journal Article | Research Support, Non-U.S. Gov't||PubMed ID: 16322523|
Topics addressed in this paper
Number of different genes curated to this paper: 10
- To go to the Locus page for a gene, click on the gene name.