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Stevenson LF, et al.  (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51

Abstract: We have undertaken an extensive screen to identify Saccharomyces cerevisiae genes whose products are involved in cell cycle progression. We report the identification of 113 genes, including 19 hypothetical ORFs, which confer arrest or delay in specific compartments of the cell cycle when overexpressed. The collection of genes identified by this screen overlaps with those identified in loss-of-function cdc screens but also includes genes whose products have not previously been implicated in cell cycle control. Through analysis of strains lacking these hypothetical ORFs, we have identified a variety of new CDC and checkpoint genes.

Status: Published Type: Journal Article PubMed ID: 11274415

Topics addressed in this paper

Number of different genes curated to this paper: 84

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Topics Topics not linked to Genes Genes linked to topics (#1 - 10 )
ABF1 ACS2 ACT1 ALO1 ARF1 ARF2 AYR1 BFA1 BIM1 BNI4
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Large-scale phenotype analysis yg ball
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Omics yg ball
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Topics Genes linked to topics (#11 - 20 )
CAJ1 CCC1 CDC14 CDC20 CDC55 CDH1 CLB2 CLB3 COA1 CST6
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#21 - 30 )
DAT1 DID2 ERV14 ERV29 FSF1 FUN14 GCN4 GFD2 GIP3 GVP36
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Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball blue ball blue ball blue ball
Strains/Constructs blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#31 - 40 )
HER1 HHO1 HSC82 ITT1 KES1 LNP1 MGA1 MGE1 MIA40 MKS1
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Function/Process blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#41 - 50 )
MNL2 MNP1 MOS2 MRT4 MSS11 MYO2 NAM8 NHP6B NOP2 PAP1
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Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Function/Process blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#51 - 60 )
PDS1 PHO87 POM33 PPH21 PPZ1 RNQ1 RPG1 RPL4A SAC3 SDS22
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball
Strains/Constructs blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#61 - 70 )
SEC4 SED5 SHO1 SKG1 SLG1 SLI15 SPC42 SPC98 SQS1 STE4
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#71 - 80 )
SVP26 TIF4631 TIM50 TPK1 TPK2 TUB1 TUB2 UBX4 UGO1 ULP1
Additional Literature blue ball blue ball blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball blue ball blue ball blue ball
Function/Process blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball
Primary Literature blue ball blue ball blue ball blue ball blue ball blue ball
Strains/Constructs blue ball blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#81 - 84 )
WWM1 YDR514C YRB1 ZDS1
Additional Literature blue ball blue ball
Cell Cycle Phase Involved blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball
Primary Literature blue ball blue ball
Strains/Constructs blue ball blue ball blue ball
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  • To go to the Locus page for a gene, click on the gene name.

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