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Takano A, et al.  (2005) tRNA actively shuttles between the nucleus and cytosol in yeast. Science 309(5731):140-2

Abstract: Previous evidence suggested that transfer RNAs (tRNAs) cross the nuclear envelope to the cytosol only once after maturing in the nucleus. We now present evidence for nuclear import of tRNAs in yeast. Several export mutants accumulate mature tRNAs in the nucleus even in the absence of transcription. Import requires energy but not the Ran cycle. These results indicate that tRNAs shuttle between the nucleus and cytosol.

Status: Published Type: Journal Article PubMed ID: 15905365

Topics addressed in this paper

Number of different genes curated to this paper: 34

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Topics Genes linked to topics (#1 - 10 )
CCA1 LOS1 MSN5 RNA1 SUF11 SUF7 SUF8 SUP11 SUP2 SUP3
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cellular Location blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball
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RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#11 - 20 )
SUP4 SUP5 SUP6 SUP7 SUP8 tI(AAU)B tI(AAU)D tI(AAU)E1 tI(AAU)E2 tI(AAU)G
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cellular Location blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball blue ball

Topics Genes linked to topics (#21 - 30 )
tI(AAU)I1 tI(AAU)I2 tI(AAU)L1 tI(AAU)L2 tI(AAU)N1 tI(AAU)N2 tI(AAU)P1 tI(AAU)P2 tP(UGG)L tP(UGG)N1
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Cellular Location blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball
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Topics Genes linked to topics (#31 - 34 )
tP(UGG)N2 tP(UGG)O1 tP(UGG)O3 TRN1
Additional Literature blue ball blue ball blue ball blue ball
Cellular Location blue ball blue ball blue ball blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball

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