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Sarin S, et al.  (2004) Uncovering novel cell cycle players through the inactivation of securin in budding yeast. Genetics 168(3):1763-71

Abstract: Budding yeast securin/Pds1p, an inhibitor of the anaphase activator separase/Esp1p, is involved in several checkpoint pathways and in promoting Esp1p's nuclear localization. Using a modified synthetic genetic array (SGA) screen for genes that become essential in the absence of Pds1p, we uncovered roles for uncharacterized genes in cell cycle processes, including Esp1p activation.

Status: Published Type: Journal Article PubMed ID: 15579722

Topics addressed in this paper

Number of different genes curated to this paper: 26

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Topics Genes linked to topics (#1 - 10 )
APQ12 CHL1 CIK1 CIN1 CIN2 CIN8 CLB2 CTF18 CTF19 CTF4
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Topics Genes linked to topics (#11 - 20 )
DCC1 DIA2 ESP1 GIM5 HCM1 HSC82 MAD2 MRC1 PDS1 QRI5
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Function/Process blue ball
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Topics Genes linked to topics (#21 - 26 )
RAD9 SLK19 SSE1 STI1 SWS2 VPS64
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Genetic Interactions blue ball blue ball blue ball blue ball blue ball blue ball
Mutants/Phenotypes blue ball blue ball blue ball blue ball blue ball blue ball
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