Maekawa H and Schiebel E (2004) CLIP-170 family members: a motor-driven ride to microtubule plus ends. Dev Cell 6(6):746-8
Abstract: CLIP-170 family proteins regulate microtubule plus end dynamics. Two reports published in this issue of Developmental Cell show that Bik1 and tip1p, the CLIP-170-like proteins of budding and fission yeast, are carried to microtubule plus ends by kinesin motor proteins. These findings indicate a complex interplay between microtubule-associated proteins and suggest a novel mechanism by which kinesin proteins stabilize microtubules.
|Status: Published||Type: Comment | Journal Article | Review | Review, Tutorial||PubMed ID: 15177023|
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