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Cook MA and Tyers M  (2004) Cellular differentiation: the violin strikes up another tune. Curr Biol 14(1):R11-3

Abstract: A switch in cellular identity in budding yeast requires the ubiquitin-dependent elimination of pre-existing master regulators encoded by the MAT locus. Failure to disassemble the prior state not only impairs the cell type transition but imparts a hybrid cellular fate. This theme will undoubtedly arise in many developmental and disease contexts.

Status: Published Type: Journal Article | Review | Review, Tutorial PubMed ID: 14711426

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HMRA1 MATA1 MATALPHA
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