Cook MA and Tyers M (2004) Cellular differentiation: the violin strikes up another tune. Curr Biol 14(1):R11-3
Abstract: A switch in cellular identity in budding yeast requires the ubiquitin-dependent elimination of pre-existing master regulators encoded by the MAT locus. Failure to disassemble the prior state not only impairs the cell type transition but imparts a hybrid cellular fate. This theme will undoubtedly arise in many developmental and disease contexts.
|Status: Published||Type: Journal Article | Review | Review, Tutorial||PubMed ID: 14711426|
Topics addressed in this paper
Number of different genes curated to this paper: 3
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