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Marchfelder U, et al.  (2003) SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae? Yeast 20(9):797-801

Abstract: The proteins Sir2, Sir3 and Sir4 repress transcription of the silent mating-type loci HML and HMR and of reporter genes inserted at telomeres. Previous microarray analyses suggested that additional non-telomeric genes exist which are repressed by the Sir proteins. In this study, we tested the expression of 12 such genes by Northern analysis and RT-PCR. However, we were unable to verify their SIR-dependent regulation, which suggests that SIR-mediated repression may be restricted to the known repressed regions.CI - Copyright 2003 John Wiley & Sons, Ltd.

Status: Published Type: Journal Article PubMed ID: 12845605

Topics addressed in this paper

Number of different genes curated to this paper: 15

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Topics Genes linked to topics (#1 - 10 )
BNA1 CRC1 CTF13 HIT1 LTV1 MTH1 NUF2 PEX17 SIR2 SIR3
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Topics Genes linked to topics (#11 - 15 )
SIR4 SNO1 SNZ1 USV1 ZRT1
Additional Literature blue ball blue ball blue ball
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Function/Process blue ball
Mutants/Phenotypes blue ball
Primary Literature blue ball blue ball
Regulation of blue ball blue ball blue ball blue ball
Regulatory Role blue ball
RNA Levels and Processing blue ball blue ball blue ball blue ball
Strains/Constructs blue ball

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