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Kim H, et al.  (2003) Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. J Biol Chem 278(12):10208-13

Abstract: We provide experimentally based topology models for 37 integral membrane proteins from Saccharomyces cerevisiae. A C-terminal fusion to a dual Suc2/His4C topology reporter has been used to determine the location of the C terminus of each protein relative to the endoplasmic reticulum membrane, and this information is used in conjunction with theoretical topology prediction methods to arrive at a final topology model. We propose that this approach may be used to produce reliable topology models on a proteome-wide scale.

Status: Published Type: Journal Article PubMed ID: 12524434

Topics addressed in this paper

Number of different genes curated to this paper: 39

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Topics Genes linked to topics (#1 - 10 )
AQY1 ASG7 ATO2 AVT6 CDC1 ECM7 ERP2 ERV15 FCY2 FLD1
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Topics Genes linked to topics (#11 - 20 )
HHY1 IZH4 MEP1 MUP1 OSW5 PAM17 PUG1 RTA1 SHR3 SNA2
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Topics Genes linked to topics (#21 - 30 )
THI74 TPO1 UIP5 VMA16 VMA21 VPH2 YDR090C YET2 YGR149W YGR290W
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Topics Genes linked to topics (#31 - 39 )
YHR140W YLR046C YLR311C YNL194C YNR062C YOL079W YOR376W YPL264C YPR071W
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Cellular Location blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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