SGD Paper 
Page Contents:
Rodriguez-Navarro S, et al. (2002) An intron in the YRA1 gene is required to control Yra1 protein expression and mRNA export in yeast. EMBO Rep 3(5):438-42
Abstract: Yra1p is an essential and conserved mRNA export factor in yeast. Strikingly, removal of the intron from YRA1 causes a dominant-negative growth phenotype and a concomitant inhibition of mRNA export. However, both defects are neutralized by replacement of the intron of YRA1 by a different intron. Significantly, Yra1p is overproduced in yeast when expressed from its intronless gene, but Yra1p levels are the same as the wild type when expressed from an intron-containing YRA1 gene. Thus, an intron in YRA1 controls Yra1p expression and mRNA export.
| Status: Published | Type: Journal Article | PubMed ID: 11964382 |
Topics addressed in this paper
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
| Topics | Genes linked to topics |
|---|---|
| YRA1 | |
| Function/Process |  |
| Mutants/Phenotypes | |
| Primary Literature | |
| Regulation of | |
| RNA Levels and Processing | |
| Strains/Constructs | |
Page Contents:
