SGD Paper Help



Zuniga S, et al.  (1999) Deletion of 24 open reading frames from chromosome XI from Saccharomyces cerevisiae and phenotypic analysis of the deletants. Gene 233(1-2):141-50

Abstract: As a part of the EUROFAN program, 24 open reading frames from Saccharomyces cerevisiae (YKR010c to YKR013w, YKR015c to YKR025w, YKR081c to YKR083c, YKR087c to YKR091w and YKR096w) were disrupted in two genetic backgrounds, FY1679 and W303. Systematic deletions and phenotypic analysis were performed following a hierarchical strategy, the so-called 'mass murder'. Of the 24 genes thus deleted, four are essential, whereas the deletion of 17 did not reveal any significant difference between the parental and mutant strains. Deletions of the remaining three show some growth phenotype; ykr024c mutants grow slowly under any conditions, ykr019c mutants grow slower in a rich medium and ykr082w mutants are temperature sensitive, being unable to germinate at 30 degrees C and above.

Status: Published Type: Journal Article PubMed ID: 10375630

Topics addressed in this paper

Number of different genes curated to this paper: 24

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Topics Genes linked to topics (#1 - 10 )
ALY1 DAD2 DBP7 ESL2 FCJ1 HEL1 IRS4 NTR2 NUP133 OMA1
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Topics Genes linked to topics (#11 - 20 )
PRY2 PXL1 RPC37 RPF2 SRL3 TGL4 TOF2 TVP38 VPS51 YKR011C
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Topics Genes linked to topics (#21 - 24 )
YKR012C YKR015C YKR018C YKR023W
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