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Maiorano D and Mechali M (2002) Many roads lead to the origin. Nat Cell Biol 4(3):E58-9
Abstract: The assembly of the DNA helicase at replication origins is crucial in initiating DNA synthesis. This process requires the conserved protein Cdt1. Here, a new study identifies a functional homologue of Cdt1 in Saccharomyces cerevisiae. The regulation of its activity reveals an alternative way to assemble prereplicative complexes (pre-RCs) and regulate origin function.
| Status: Published | Type: Journal Article | PubMed ID: 11875449 |
Topics addressed in this paper
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| Topics | Genes linked to topics |
|---|---|
| TAH11 | |
| Function/Process | |
| Fungal Related Genes/Proteins | |
| Non-Fungal Related Genes/Proteins | |
| Primary Literature | |
| Regulation of | |
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