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Connolly CM and Sandmeyer SB  (1997) RNA polymerase III interferes with Ty3 integration. FEBS Lett 405(3):305-11

Abstract: Ty3, a gypsylike retrotransposon of budding yeast, integrates at the transcription initiation site of genes transcribed by RNA polymerase III (pol III). It was previously shown that integration in vitro requires intact promoter elements and the pol III transcription factors TFIIIB and TFIIIC. In order to test the effect of pol III on integration, increasing amounts of a pol III-containing fraction were added to Ty3 in vitro integration reactions. The pol III-containing fraction was inhibitory to integration. These results are consistent with a model where the Ty3 integration complex and pol III recognize similar features of the stable transcription complex and compete with each other for access to the transcription initiation site.

Status: Published Type: Journal Article PubMed ID: 9108309

Topics addressed in this paper

Number of different genes curated to this paper: 27

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Topics Genes linked to topics (#1 - 10 )
BDP1 BRF1 RET1 RPB10 RPB5 RPB8 RPC10 RPC17 RPC19 RPC25
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Topics Genes linked to topics (#11 - 20 )
RPC31 RPC34 RPC37 RPC40 RPC53 RPC82 RPO26 RPO31 SPT15 TFC1
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Topics Genes linked to topics (#21 - 27 )
TFC3 TFC4 TFC6 TFC7 TFC8 YGRWTy3-1 YILWTy3-1
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Function/Process blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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