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Braun BR, et al.  (1992) Topography of transcription factor complexes on the Saccharomyces cerevisiae 5 S RNA gene. J Mol Biol 228(4):1063-77

Abstract: Locations of component proteins of yeast RNA polymerase III transcription factors (TFIII) A, C and B on a 5 S rRNA gene have been determined by site-specific DNA-protein photo-crosslinking. Comparison with a previously analyzed tRNA gene shows that similar nucleoprotein structures assemble on these two genes despite their differently located internal promoter elements. A principal signature of this homology is the placement of the 95 kDA subunit of TFIIIC, which associates with the box A promoter element of the tRNA gene. On the 5 S rRNA gene, the 95 kDa subunit occupies the same space in the absence of a box A sequence, and despite the presence of a box A-like sequence 30 base-pairs further downstream. A 90 kDa component that was not previously recognized as an integral part of TFIIIC has been specifically located at the 3' end of the 5 S rRNA gene.

Status: Published Type: Journal Article PubMed ID: 1474578

Topics addressed in this paper

Number of different genes curated to this paper: 15

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Topics Genes linked to topics (#1 - 10 )
BDP1 BRF1 PZF1 RDN5-1 RDN5-2 RDN5-3 RDN5-4 RDN5-5 RDN5-6 TFC1
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Topics Genes linked to topics (#11 - 15 )
TFC3 TFC4 TFC6 TFC7 TFC8
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Protein-Nucleic Acid Interactions blue ball blue ball blue ball
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