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Yudkovsky N, et al.  (1999) Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators. Genes Dev 13(18):2369-74

Abstract: SWI/SNF is a chromatin remodeling complex that facilitates expression of a number of yeast genes. Here we demonstrate that SWI/SNF can be recruited from yeast nuclear extracts by a transcriptional activator. Recruitment is dependent on an activation domain but not on promoter sequences, TBP, or RNA polymerase II holoenzyme. We also show that acidic activation domains can target SWI/SNF remodeling activity. These results demonstrate that SWI/SNF activity can be targeted by gene-specific activators and that this recruitment can occur independently of Pol II holoenzyme.

Status: Published Type: Journal Article PubMed ID: 10500094

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ARP7 ARP9 GAL11 RPB3 SNF11 SNF12 SNF2 SNF5 SNF6 SPT15
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Topics Genes linked to topics (#11 - 17 )
SRB2 SRB4 SUA7 SWI1 SWI3 TAF14 TOA2
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