SGD Paper 
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Edqvist J, et al. (1993) Pleiotrophic effects of point mutations in yeast tRNA(Asp) on the base modification pattern. Nucleic Acids Res 21(3):413-7
Abstract: The base-modification pattern has been studied in several synthetic variants of yeast tRNA(Asp) injected into Xenopus laevis oocytes. Certain point mutations in the D-stem and the variable loop of the tRNA led to considerably decreased levels of m1G37, psi 40 and Q34/manQ34 in the anticodon stem or loop and an increased rate of synthesis for m5C49 in the T-stem. The formation of m2G6 in the aminoacyl-stem was not affected in any of the tRNA-variants. Thus, mutations in one part of the tRNA-molecule can have long-range effects on the interactions between another part of the tRNA and the tRNA modifying enzymes.
| Status: Published | Type: Journal Article | PubMed ID: 8441654 |
Topics addressed in this paper
Number of different genes curated to this paper: 17
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| tD(GUC)B | tD(GUC)D | tD(GUC)G1 | tD(GUC)G2 | tD(GUC)I1 | tD(GUC)I2 | tD(GUC)J1 | tD(GUC)J2 | tD(GUC)J3 | tD(GUC)J4 | |
| Additional Literature |  | | | | | | | | | |
| DNA/RNA Sequence Features | | | | | | | | | | |
| Topics | Genes linked to topics (#11 - 17 ) | ||||||
|---|---|---|---|---|---|---|---|
| tD(GUC)K | tD(GUC)L1 | tD(GUC)L2 | tD(GUC)M | tD(GUC)N | tD(GUC)O | tD(GUC)Q | |
| Additional Literature | | | | | | | |
| DNA/RNA Sequence Features | | | | | | | |
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