Shams-Eldin H, et al. (2001) The Schizosaccharomyces pombe GPI8 gene complements a Saccharomyces cerevisiae GPI8 anchoring mutant. Yeast 18(1):33-9
Abstract: The final step in glycosylphosphatidylinositol (GPI) anchoring of cell surface proteins consists of a transamidation reaction, in which preassembled GPI donors are substituted for C-terminal signal sequences in nascent polypeptides. The Saccharomyces cerevisiae GPI8 gene (ScGPI8) encodes a protein which is involved in the GPI transamidation reaction. We have cloned and isolated the Schizosaccharomyces pombe GPI8 homologous gene (SpGPI8). The SpGPI8 gene encodes a protein of 411 amino acids witha calculated molecular weight of about 47 kDa. It shows 53.5% identity with the ScGPI8 and complements a S. cerevisiae GPI8 anchoring mutant. The nucleotide sequence data reported in this paper appears in the EMBL Data Bank nucleotide sequence database with Accession No. AJ250428. Copyright 2000 John Wiley & Sons, Ltd.
|Status: Published||Type: Journal Article||PubMed ID: 11124699|
Topics addressed in this paper
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|Fungal Related Genes/Proteins|