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Treger JM, et al.  (1998) Transcriptional factor mutations reveal regulatory complexities of heat shock and newly identified stress genes in Saccharomyces cerevisiae. J Biol Chem 273(41):26875-9

Abstract: A computer-aided pattern search of the entire yeast genome was designed and used to identify 186 putative stress response element-regulated genes in Saccharomyces cerevisiae. Transcript levels of eight of these candidate genes were examined, and three (37%) were shown to be heat shock- and DNA damage-inducible and to require the Msn2p and Msn4p transcriptional activators for stress regulation. Significantly, several heat shock protein (HSP) genes were identified in this computer search. Using a series of single and multiple regulatory mutants, we demonstrate unexpected regulatory complexities among the HSP genes from S. cerevisiae following heat shock.

Status: Published Type: Journal Article PubMed ID: 9756934

Topics addressed in this paper

Number of different genes curated to this paper: 20

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Topics Genes linked to topics (#1 - 10 )
HSF1 HSP104 HSP12 HSP26 HSP42 HSP78 HSP82 MSN2 MSN4 PDE2
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DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#11 - 20 )
PGM2 RAS2 RPA14 RPB4 RPH1 SMC2 SSA3 UBI4 YGR067C YKL151C
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DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Mutants/Phenotypes blue ball
Primary Literature blue ball
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