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Haro R, et al. (1991) A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett 291(2):189-91
Abstract: The gene ENA1 was cloned by its ability to complement the Li+ sensitivity of a low Li(+)-efflux strain. The nucleotide sequence of the cloned DNA fragment showed that there are two almost identical genes in tandem, and predicts that they encode P-ATPases. Disruption of both genes originated a strain defective in Na+ and Li+ effluxes, and sensitive to Na+, to Li+ and to alkaline pH. By transformation with ENA1 the defective effluxes and tolerances were repaired.
| Status: Published | Type: Journal Article | PubMed ID: 1657642 |
Topics addressed in this paper
Number of different genes curated to this paper: 2
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