Balakin AG, et al. (1996) The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell 86(5):823-34
Abstract: We have discovered that all known yeast and vertebrate small nucleolar RNAs (snoRNAs), except for the MRP/7-2 RNA, fall into two major classes. One class is defined by conserved boxes C and D and the other by a novel element: a consensus ACA triplet positioned 3 nt before the 3' end of the RNA. A role for the ACA box is snoRNA stability has been established by mutational analysis of a yeast ACA snoRNA (snR 11). Full function of the box depends on the integrity of an adjacent upstream stem. All members of the yeast ACA family are associated with the GAR1 protein. Binding of this or another common small nucleolar ribonucleoprotein particle protein is predicted to be a critical entry point to snoRNA posttranscriptional life, including precise formation of the snoRNA 3' end.
| Status: Published | Type: Journal Article | PubMed ID: 8797828 |
Topics addressed in this paper
Number of different genes curated to this paper: 37
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| Topics | Genes linked to topics (#1 - 10 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GAR1 | NME1 | SNR10 | SNR11 | SNR128 | SNR13 | SNR17A | SNR17B | SNR18 | SNR189 | |
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| DNA/RNA Sequence Features | | | | | | | | | | |
| Function/Process | | |||||||||
| Non-Fungal Related Genes/Proteins | | | | | | |||||
| Protein-Nucleic Acid Interactions | | |||||||||
| Topics | Genes linked to topics (#11 - 20 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SNR190 | SNR24 | SNR3 | SNR30 | SNR31 | SNR32 | SNR33 | SNR34 | SNR35 | SNR36 | |
| Additional Literature | | | | | | | | | | |
| DNA/RNA Sequence Features | | | | | | | | | | |
| Non-Fungal Related Genes/Proteins | | |||||||||
| Protein-Nucleic Acid Interactions | | |||||||||
| Topics | Genes linked to topics (#21 - 30 ) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SNR37 | SNR38 | SNR39 | SNR4 | SNR40 | SNR41 | SNR42 | SNR43 | SNR44 | SNR45 | |
| Additional Literature | | | | | | | | | | |
| DNA/RNA Sequence Features | | | | | | | | | | |
- To find other papers on a gene and topic, click on the colored ball in the appropriate box.
- displays other papers with information about that topic for that gene.
- displays other papers in SGD that are associated with that topic.
The topic is addressed in these papers but does not describe a specific gene or chromosomal feature.
- To go to the Locus page for a gene, click on the gene name.
| Topics | Genes linked to topics (#31 - 37 ) | ||||||
|---|---|---|---|---|---|---|---|
| SNR46 | SNR47 | SNR48 | SNR49 | SNR5 | SNR8 | SNR9 | |
| Additional Literature | | | | | | | |
| DNA/RNA Sequence Features | | | | | | | |




