SGD Paper Help



Balakin AG, et al.  (1996) The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell 86(5):823-34

Abstract: We have discovered that all known yeast and vertebrate small nucleolar RNAs (snoRNAs), except for the MRP/7-2 RNA, fall into two major classes. One class is defined by conserved boxes C and D and the other by a novel element: a consensus ACA triplet positioned 3 nt before the 3' end of the RNA. A role for the ACA box is snoRNA stability has been established by mutational analysis of a yeast ACA snoRNA (snR 11). Full function of the box depends on the integrity of an adjacent upstream stem. All members of the yeast ACA family are associated with the GAR1 protein. Binding of this or another common small nucleolar ribonucleoprotein particle protein is predicted to be a critical entry point to snoRNA posttranscriptional life, including precise formation of the snoRNA 3' end.

Status: Published Type: Journal Article PubMed ID: 8797828

Topics addressed in this paper

Number of different genes curated to this paper: 37

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Topics Genes linked to topics (#1 - 10 )
GAR1 NME1 SNR10 SNR11 SNR128 SNR13 SNR17A SNR17B SNR18 SNR189
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Function/Process blue ball
Non-Fungal Related Genes/Proteins blue ball blue ball blue ball blue ball blue ball
Protein-Nucleic Acid Interactions blue ball

Topics Genes linked to topics (#11 - 20 )
SNR190 SNR24 SNR3 SNR30 SNR31 SNR32 SNR33 SNR34 SNR35 SNR36
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
Non-Fungal Related Genes/Proteins blue ball
Protein-Nucleic Acid Interactions blue ball

Topics Genes linked to topics (#21 - 30 )
SNR37 SNR38 SNR39 SNR4 SNR40 SNR41 SNR42 SNR43 SNR44 SNR45
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball blue ball
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Topics Genes linked to topics (#31 - 37 )
SNR46 SNR47 SNR48 SNR49 SNR5 SNR8 SNR9
Additional Literature blue ball blue ball blue ball blue ball blue ball blue ball blue ball
DNA/RNA Sequence Features blue ball blue ball blue ball blue ball blue ball blue ball blue ball

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