PRP8/YHR165C Literature Guide Help

Other names published for PRP8: DBF3, DNA39, RNA8, SLT21, USA2, YHR165C

PRP8 - All Curated References (154)

ReferenceOther Genes Addressed
Dreumont N and Seraphin B  (2013) Rapid screening of yeast mutants with reporters identifies new splicing phenotypes. FEBS J ()
Fourmann JB, et al.  (2013) Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes Dev 27(4):413-28
Galej WP, et al.  (2013) Crystal structure of Prp8 reveals active site cavity of the spliceosome. Nature 493(7434):638-43
Li X, et al.  (2013) Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly. Nucleic Acids Res 41(6):3805-18
Query CC and Konarska MM  (2013) Structural biology: Spliceosome's core exposed. Nature 493(7434):615-6
Weber G, et al.  (2013) Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev 27(5):525-40
Chen HC and Cheng SC  (2012) Functional roles of protein splicing factors. Biosci Rep 32(4):345-59
Mozaffari-Jovin S, et al.  (2012) The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes Dev 26(21):2422-34
Ohrt T, et al.  (2012) Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS. RNA 18(6):1244-56
Query CC and Konarska MM  (2012) CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome. RNA 18(5):1001-13
Schmitzova J and Pena V  (2012) Emerging views about the molecular structure of the spliceosomal catalytic center. RNA Biol 9(11):1311-8
Chanarat S, et al.  (2011) The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes. Genes Dev 25(11):1147-58
Dlakic M and Mushegian A  (2011) Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase. RNA 17(5):799-808
Gandhi SJ, et al.  (2011) Transcription of functionally related constitutive genes is not coordinated. Nat Struct Mol Biol 18(1):27-34
Horowitz DS  (2011) The mechanism of the second step of pre-mRNA splicing. Wiley Interdiscip Rev RNA 3(3):331-50
Ren L, et al.  (2011) Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19. PLoS One 6(2):e16719
Schwer B, et al.  (2011) Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1? cells. Nucleic Acids Res 39(15):6715-28
Weber G, et al.  (2011) Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev 25(15):1601-12
Alexander RD, et al.  (2010) Splicing-dependent RNA polymerase pausing in yeast. Mol Cell 40(4):582-93
Lardelli RM, et al.  (2010) Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing. RNA 16(3):516-28
Lionnet T, et al.  (2010) Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. Cold Spring Harb Symp Quant Biol 75():113-26
Taoka M, et al.  (2010) In-Gel Digestion for Mass Spectrometric Characterization of RNA from Fluorescently Stained Polyacrylamide Gels. Anal Chem 82(18):7795-7803
Towns KV, et al.  (2010) Prognosis for splicing factor PRPF8 retinitis pigmentosa, novel mutations and correlation between human and yeast phenotypes. Hum Mutat 31(5):E1361-76
Will CL and Luhrmann R  (2010) Spliceosome Structure and Function.LID - cshperspect.a003707v1 [pii]LID - 10.1101/cshperspect.a003707 [doi] Cold Spring Harb Perspect Biol ()
Bergkessel M, et al.  (2009) SnapShot: Formation of mRNPs. Cell 136(4):794, 794.e1
Brow DA  (2009) Eye on RNA unwinding. Nat Struct Mol Biol 16(1):7-8
Fabrizio P, et al.  (2009) The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome. Mol Cell 36(4):593-608
Grainger RJ, et al.  (2009) Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. RNA 15(12):2161-73
Kershaw CJ, et al.  (2009) Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8. RNA 15(7):1292-304
Khanna M, et al.  (2009) A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. RNA 15(12):2174-85