COX2/Q0250 Literature Guide Help

Other names published for COX2: OXI1, OXII, cytochrome c oxidase subunit 2, Q0250

COX2 - Translational Regulation (31)

ReferenceOther Genes Addressed
Barros MH, et al.  (2011) Characterization of Gtf1p, the connector subunit of yeast mitochondrial tRNA-dependent amidotransferase. J Biol Chem 286(38):32937-47
Anderson SL, et al.  (2005) Analysis of interactions with mitochondrial mRNA using mutant forms of yeast NAD(+)-specific isocitrate dehydrogenase. Biochemistry 44(50):16776-84
Fiori A, et al.  (2005) Overexpression of the COX2 translational activator, Pet111p, prevents translation of COX1 mRNA and cytochrome c oxidase assembly in mitochondria of Saccharomyces cerevisiae. Mol Microbiol 56(6):1689-704
Margeot A, et al.  (2005) Why are many mRNAs translated to the vicinity of mitochondria: a role in protein complex assembly? Gene 354():64-71
Naithani S, et al.  (2003) Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae. Mol Biol Cell 14(1):324-33
Williams EH and Fox TD  (2003) Antagonistic signals within the COX2 mRNA coding sequence control its translation in Saccharomyces cerevisiae mitochondria. RNA 9(4):419-31
Green-Willms NS, et al.  (2001) Pet111p, an inner membrane-bound translational activator that limits expression of the Saccharomyces cerevisiae mitochondrial gene COX2. J Biol Chem 276(9):6392-7
Ostrander DB, et al.  (2001) Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondria. J Biol Chem 276(27):25262-72
Stribinskis V, et al.  (2001) Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase. Genetics 158(2):573-85
Bonnefoy N and Fox TD  (2000) In vivo analysis of mutated initiation codons in the mitochondrial COX2 gene of Saccharomyces cerevisiae fused to the reporter gene ARG8m reveals lack of downstream reinitiation. Mol Gen Genet 262(6):1036-46
Costanzo MC, et al.  (2000) Highly diverged homologs of Saccharomyces cerevisiae mitochondrial mRNA-specific translational activators have orthologous functions in other budding yeasts. Genetics 154(3):999-1012
Green-Willms NS, et al.  (1998) Functional interactions between yeast mitochondrial ribosomes and mRNA 5' untranslated leaders. Mol Cell Biol 18(4):1826-34
Sanchirico ME, et al.  (1998) Accumulation of mitochondrially synthesized Saccharomyces cerevisiae Cox2p and Cox3p depends on targeting information in untranslated portions of their mRNAs. EMBO J 17(19):5796-804
Dunstan HM, et al.  (1997) In vivo analysis of Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader functions in mitochondrial translation initiation and translational activation. Genetics 147(1):87-100
Torello AT, et al.  (1997) Deletion of the leader peptide of the mitochondrially encoded precursor of Saccharomyces cerevisiae cytochrome c oxidase subunit II. Genetics 145(4):903-10
Fox TD  (1996) Genetic strategies for identification of mitochondrial translation factors in Saccharomyces cerevisiae. Methods Enzymol 264:228-37
Mulero JJ and Fox TD  (1994) Reduced but accurate translation from a mutant AUA initiation codon in the mitochondrial COX2 mRNA of Saccharomyces cerevisiae. Mol Gen Genet 242(4):383-90
Mulero JJ, et al.  (1994) PET112, a Saccharomyces cerevisiae nuclear gene required to maintain rho+ mitochondrial DNA. Curr Genet 25(4):299-304
Pinkham JL, et al.  (1994) T7 RNA polymerase-dependent expression of COXII in yeast mitochondria. Mol Cell Biol 14(7):4643-52
Mulero JJ and Fox TD  (1993) Alteration of the Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader by mitochondrial gene replacement and functional interaction with the translational activator protein PET111. Mol Biol Cell 4(12):1327-35
Mulero JJ and Fox TD  (1993) PET111 acts in the 5'-leader of the Saccharomyces cerevisiae mitochondrial COX2 mRNA to promote its translation. Genetics 133(3):509-16
Pel HJ, et al.  (1992) The yeast nuclear gene MRF1 encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects. Nucleic Acids Res 20(23):6339-46
Dekker PJ, et al.  (1991) Properties of an abundant RNA-binding protein in yeast mitochondria. Biochimie 73(12):1487-92
Kloeckener-Gruissem B, et al.  (1987) Nuclear functions required for cytochrome c oxidase biogenesis in Saccharomyces cerevisiae: multiple trans-acting nuclear genes exert specific effects on expression of each of the cytochrome c oxidase subunits encoded on mitochondrial DNA. Curr Genet 12(5):311-22
Poutre CG and Fox TD  (1987) PET111, a Saccharomyces cerevisiae nuclear gene required for translation of the mitochondrial mRNA encoding cytochrome c oxidase subunit II. Genetics 115(4):637-47
McKee EE and Poyton RO  (1984) Mitochondrial gene expression in saccharomyces cerevisiae. I. Optimal conditions for protein synthesis in isolated mitochondria. J Biol Chem 259(14):9320-31
McKee EE, et al.  (1984) Mitochondrial gene expression in saccharomyces cerevisiae. II. Fidelity of translation in isolated mitochondria from wild type and respiratory-deficient mutant cells. J Biol Chem 259(14):9332-8
Macino G, et al.  (1979) Use of the UGA terminator as a tryptophan codon in yeast mitochondria. Proc Natl Acad Sci U S A 76(8):3784-5
Charalampous FC and Chen WL  (1974) Anaerobic synthesis of apocytochrome oxidase and assembly of the holoenzyme in yeast protoplasts. J Biol Chem 249(4):1007-13
Mason TL and Schatz G  (1973) Cytochrome c oxidase from bakers' yeast. II. Site of translation of the protein components. J Biol Chem 248(4):1355-60