KAR2/YJL034W Literature Guide Help

Other names published for KAR2: GRP78, BIP, Hsp70 family ATPase KAR2, YJL034W

KAR2 - Transcription (22)

ReferenceOther Genes Addressed
Patil A, et al.  (2012) Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications. RNA Biol 9(7):990-1001
Baumann K, et al.  (2011) The impact of oxygen on the transcriptome of recombinant S. cerevisiae and P. pastoris - a comparative analysis. BMC Genomics 12(1):218
Bleve G, et al.  (2011) Over-expression of functional Saccharomyces cerevisiae GUP1, induces proliferation of intracellular membranes containing ER and Golgi resident proteins. Biochim Biophys Acta 1808(3):733-44
Kumar C, et al.  (2011) Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control. EMBO J 30(10):2044-56
Gardarin A, et al.  (2010) Endoplasmic reticulum is a major target of cadmium toxicity in yeast. Mol Microbiol 76(4):1034-48
Lin FM, et al.  (2009) Comparative proteomic analysis of tolerance and adaptation of ethanologenic Saccharomyces cerevisiae to furfural, a lignocellulosic inhibitory compound. Appl Environ Microbiol 75(11):3765-76
Parikh BA, et al.  (2008) Ricin Inhibits Activation of the Unfolded Protein Response by Preventing Splicing of the HAC1 mRNA. J Biol Chem 283(10):6145-53
Jesch SA, et al.  (2006) Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms. J Biol Chem 281(33):24070-83
Kumar A, et al.  (2006) Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast. Biochem J 396(1):61-9
Matsumoto R, et al.  (2005) The stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiae. BMC Genomics 6():141
Seppa L and Makarow M  (2005) Regulation and recovery of functions of Saccharomyces cerevisiae chaperone BiP/Kar2p after thermal insult. Eukaryot Cell 4(12):2008-16
Ichimura T, et al.  (2004) Transcriptomic and proteomic analysis of a 14-3-3 gene-deficient yeast. Biochemistry 43(20):6149-58
Ogawa N and Mori K  (2004) Autoregulation of the HAC1 gene is required for sustained activation of the yeast unfolded protein response. Genes Cells 9(2):95-104
Norgaard P, et al.  (2003) Gene regulation in response to protein disulphide isomerase deficiency. Yeast 20(7):645-52
Valkonen M, et al.  (2003) Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 69(4):2065-72
Song Y, et al.  (2002) Different effects of calnexin deletion in Saccharomyces cerevisiae on the secretion of two glycosylated amyloidogenic lysozymes. FEBS Lett 512(1-3):213-7
Zimmer T, et al.  (1999) Misfolded membrane-bound cytochrome P450 activates KAR2 induction through two distinct mechanisms. J Biochem 126(6):1080-9
Menzel R, et al.  (1997) Inducible membranes in yeast: relation to the unfolded-protein-response pathway. Yeast 13(13):1211-29
Oka M, et al.  (1997) Saccharomyces cerevisiae KAR2 (BiP) gene expression is induced by loss of cytosolic HSP70/Ssa1p through a heat shock element-mediated pathway. J Biochem 121(3):578-84
Nikawa J, et al.  (1996) Saccharomyces cerevisiae IRE2/HAC1 is involved in IRE1-mediated KAR2 expression. Nucleic Acids Res 24(21):4222-6
Robinson AS, et al.  (1996) Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae. J Biol Chem 271(17):10017-22
Robinson AS and Wittrup KD  (1995) Constitutive overexpression of secreted heterologous proteins decreases extractable BiP and protein disulfide isomerase levels in Saccharomyces cerevisiae. Biotechnol Prog 11(2):171-7