KEX2/YNL238W Literature Guide Help

Other names published for KEX2: QDS1, VMA45, SRB1, kexin, yscF, YNL238W

KEX2 - Techniques and Reagents (32)

ReferenceOther Genes Addressed
Bader O, et al.  (2008) Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol 8:116
Han HE, et al.  (2005) Engineering of Kex2 variants exhibiting altered substrate specificity. Biochem Biophys Res Commun 337(4):1102-6
Brickner JH, et al.  (2001) The Tlg SNARE complex is required for TGN homotypic fusion. J Cell Biol 155(6):969-78
Hopkins BD, et al.  (2000) Introduction of Kex2 cleavage sites in fusion proteins for monitoring localization and transport in yeast secretory pathway. Methods Enzymol 327:107-18
Kjeldsen T  (2000) Yeast secretory expression of insulin precursors. Appl Microbiol Biotechnol 54(3):277-86
Kohno M, et al.  (2000) Thermal stability of Rhizopus niveus lipase expressed in a kex2 mutant yeast. J Biotechnol 81(2-3):141-50
Molina M, et al.  (2000) Protein localisation approaches for understanding yeast cell wall biogenesis. Microsc Res Tech 51(6):601-12
Rockwell NC, et al.  (2000) Synthesis of peptidyl methylcoumarin esters as substrates and active-site titrants for the prohormone processing proteases Kex2 and PC2. Anal Biochem 280(2):201-8
Chen CY, et al.  (1999) Role for Drs2p, a P-type ATPase and potential aminophospholipid translocase, in yeast late Golgi function. J Cell Biol 147(6):1223-36
Greenfield JP, et al.  (1999) Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein. J Biol Chem 274(48):33843-6
Henkel MK, et al.  (1999) Endocytic delivery of intramolecularly quenched substrates and inhibitors to the intracellular yeast Kex2 protease1. Biochem J 341 ( Pt 2)():445-52
Lee J, et al.  (1999) Novel secretion system of recombinant Saccharomyces cerevisiae using an N-terminus residue of human IL-1 beta as secretion enhancer. Biotechnol Prog 15(5):884-90
Ossipov D, et al.  (1999) Yeast ER-Golgi v-SNAREs Bos1p and Bet1p differ in steady-state localization and targeting. J Cell Sci 112 ( Pt 22):4135-42
Takahashi S, et al.  (1999) Independent production of two molecular forms of a recombinant Rhizopus oryzae lipase by KEX2-engineered strains of Saccharomyces cerevisiae. Appl Microbiol Biotechnol 52(4):534-40
Werten MW, et al.  (1999) High-yield secretion of recombinant gelatins by Pichia pastoris. Yeast 15(11):1087-96
Kjeldsen T, et al.  (1998) Prepro-leaders lacking N-linked glycosylation for secretory expression in the yeast Saccharomyces cerevisiae. Protein Expr Purif 14(3):309-16
Bessmertnaya LYa, et al.  (1997) Specific cleavage of hybrid proteins by proteinase encoded by the KEX2 gene. Biochemistry (Mosc) 62(8):850-7
Stepp JD, et al.  (1997) The yeast adaptor protein complex, AP-3, is essential for the efficient delivery of alkaline phosphatase by the alternate pathway to the vacuole. J Cell Biol 139(7):1761-74
Bryant NJ and Boyd A  (1995) Localization of a protein A-tagged Kex2 protein to the vacuole of Saccharomyces cerevisiae allows rapid purification of vacuolar membranes. Yeast 11(3):201-10
Boehm J, et al.  (1994) Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER-->Golgi transport in yeast. EMBO J 13(16):3696-710
Bourbonnais Y, et al.  (1994) Cleavage of prosomatostatins by the yeast Yap3 and Kex2 endoprotease. Biochimie 76(3-4):226-33
Brenner C, et al.  (1994) Biochemical and genetic methods for analyzing specificity and activity of a precursor-processing enzyme: yeast Kex2 protease, kexin. Methods Enzymol 244:152-67
Moulard M, et al.  (1994) Kex2p: a model for cellular endoprotease processing human immunodeficiency virus type 1 envelope glycoprotein precursor. Eur J Biochem 225(2):565-72
Whitters EA, et al.  (1994) Purification and characterization of a late Golgi compartment from Saccharomyces cerevisiae. J Biol Chem 269(45):28106-17
Bryant NJ and Boyd A  (1993) Immunoisolation of Kex2p-containing organelles from yeast demonstrates colocalisation of three processing proteinases to a single Golgi compartment. J Cell Sci 106 ( Pt 3)():815-22
Brenner C and Fuller RS  (1992) Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease. Proc Natl Acad Sci U S A 89(3):922-6
Chaudhuri B and Stephan C  (1992) A modified Kex2 enzyme retained in the endoplasmic reticulum prevents disulfide-linked dimerisation of recombinant human insulin-like growth factor-1 secreted from yeast. FEBS Lett 304(1):41-5
Chaudhuri B, et al.  (1992) A mutant Kex2 enzyme with a C-terminal HDEL sequence releases correctly folded human insulin-like growth factor-1 from a precursor accumulated in the yeast endoplasmic reticulum. Eur J Biochem 210(3):811-22
Germain D, et al.  (1992) Expression of the Saccharomyces cerevisiae Kex2p endoprotease in inset cells. Evidence for a carboxy-terminal autoprocessing event. Eur J Biochem 204(1):121-6
Zollinger L, et al.  (1990) Intracellular proteolytic processing of proopiomelanocortin in heterologous COS-1 cells by the yeast KEX2 endoprotease. Biochem Cell Biol 68(3):635-40