TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Techniques and Reagents (13)

ReferenceOther Genes Addressed
Schmidt BH, et al.  (2010) A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases. Nature 465(7298):641-4
Baldwin M and Bachant J  (2009) Top2 SUMO Conjugation in Yeast Cell Lysates. Methods Mol Biol 582:209-19
Baldwin M, et al.  (2009) Analyzing top2 distribution on yeast chromosomes by chromatin immunoprecipitation. Methods Mol Biol 582:119-30
Bermejo R, et al.  (2009) ChIP-on-Chip Analysis of DNA Topoisomerases. Methods Mol Biol 582:103-18
Takahashi Y and Strunnikov A  (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98
Schultz MC  (1999) Chromatin assembly in yeast cell-free extracts. Methods 17(2):161-72
Liu Q and Wang JC  (1998) Identification of active site residues in the "GyrA" half of yeast DNA topoisomerase II. J Biol Chem 273(32):20252-60
Rodriguez-Campos A  (1996) DNA knotting abolishes in vitro chromatin assembly. J Biol Chem 271(24):14150-5
Roca J, et al.  (1994) Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp. Proc Natl Acad Sci U S A 91(5):1781-5
Wasserman RA, et al.  (1993) Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast. Cancer Res 53(15):3591-6
Chung IK and Muller MT  (1991) Aggregates of oligo(dG) bind and inhibit topoisomerase II activity and induce formation of large networks. J Biol Chem 266(15):9508-14
Figgitt DP, et al.  (1989) Topoisomerase II: a potential target for novel antifungal agents. Biochem Biophys Res Commun 160(1):257-62
Goto T, et al.  (1984) The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae. J Biol Chem 259(16):10422-9