RAD50/YNL250W Literature Guide Help

Other names published for RAD50: YNL250W

RAD50 - Substrates/Ligands/Cofactors (22)

ReferenceOther Genes Addressed
Niu H, et al.  (2010) Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. Nature 467(7311):108-11
Steininger S, et al.  (2010) A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair. Nucleic Acids Res 38(6):1853-65
Westmoreland J, et al.  (2009) RAD50 Is Required for Efficient Initiation of Resection and Recombinational Repair at Random, gamma-Induced Double-Strand Break Ends. PLoS Genet 5(9):e1000656
Bhaskara V, et al.  (2007) Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes. Mol Cell 25(5):647-61
Ghosal G and Muniyappa K  (2007) The Characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 Complex Reveals that Rad50 Negatively Regulates Mre11 Endonucleolytic but not the Exonucleolytic Activity. J Mol Biol 372(4):864-82
Lengsfeld BM, et al.  (2007) Sae2 Is an Endonuclease that Processes Hairpin DNA Cooperatively with the Mre11/Rad50/Xrs2 Complex. Mol Cell 28(4):638-51
Chen L, et al.  (2005) Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. J Biol Chem 280(4):2620-7
Yoshida J, et al.  (2003) Positive and negative roles of homologous recombination in the maintenance of genome stability in Saccharomyces cerevisiae. Genetics 164(1):31-46
Freedman JA and Jinks-Robertson S  (2002) Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. Genetics 162(1):15-27
Ira G and Haber JE  (2002) Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequences. Mol Cell Biol 22(18):6384-92
Lewis LK, et al.  (2002) Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160(1):49-62
Manthey GM and Bailis AM  (2002) Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol 22(15):5347-56
Chen L, et al.  (2001) Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol Cell 8(5):1105-15
McVey M, et al.  (2001) The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics 157(4):1531-42
Trujillo KM and Sung P  (2001) DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. J Biol Chem 276(38):35458-64
van Attikum H, et al.  (2001) Non-homologous end-joining proteins are required for Agrobacterium T-DNA integration. EMBO J 20(22):6550-8
Nasar F, et al.  (2000) Long palindromic sequences induce double-strand breaks during meiosis in yeast. Mol Cell Biol 20(10):3449-58
Rattray AJ, et al.  (2000) The Saccharomyces cerevisiae DNA recombination and repair functions of the RAD52 epistasis group inhibit Ty1 transposition. Genetics 154(2):543-56
Simon JA, et al.  (2000) Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60(2):328-33
You JC  (2000) The effects of RAD52 epistasis group genes on various types of spontaneous mitotic recombination in Saccharomyces cerevisiae. Biochem Biophys Res Commun 270(1):112-8
Kironmai KM and Muniyappa K  (1997) Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae. Genes Cells 2(7):443-55
de Massy B, et al.  (1995) The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae. EMBO J 14(18):4589-98