IRE1/YHR079C Literature Guide Help

Other names published for IRE1: ERN1, YHR079C

IRE1 - Substrates/Ligands/Cofactors (15)

ReferenceOther Genes Addressed
Lajoie P, et al.  (2012) Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells. Mol Biol Cell 23(5):955-64
Chawla A, et al.  (2011) Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase. J Cell Biol 193(1):41-50
Wiseman RL, et al.  (2010) Flavonol activation defines an unanticipated ligand-binding site in the kinase-RNase domain of IRE1. Mol Cell 38(2):291-304
Lee KP, et al.  (2008) Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing. Cell 132(1):89-100
Niwa M, et al.  (2005) Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease. Genome Biol 6(1):R3
Ptacek J, et al.  (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84
Kimata Y, et al.  (2003) Genetic evidence for a role of BiP/Kar2 that regulates Ire1 in response to accumulation of unfolded proteins. Mol Biol Cell 14(6):2559-69
Papa FR, et al.  (2003) Bypassing a kinase activity with an ATP-competitive drug. Science 302(5650):1533-7
Haynes CM, et al.  (2002) An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport. J Cell Biol 158(1):91-101
Dong B, et al.  (2001) Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p. RNA 7(3):361-73
Casagrande R, et al.  (2000) Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway. Mol Cell 5(4):729-35
Zhu H, et al.  (2000) Analysis of yeast protein kinases using protein chips. Nat Genet 26(3):283-9
Gonzalez TN, et al.  (1999) Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J 18(11):3119-32
Sidrauski C and Walter P  (1997) The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response. Cell 90(6):1031-9
Cox JS and Walter P  (1996) A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response. Cell 87(3):391-404