APN1/YKL114C Literature Guide Help

Other names published for APN1: DNA-(apurinic or apyrimidinic site) lyase APN1, YKL114C

APN1 - Substrates/Ligands/Cofactors (20)

ReferenceOther Genes Addressed
Morris LP, et al.  (2012) Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. DNA Repair (Amst) 11(9):753-65
Redrejo-Rodriguez M, et al.  (2011) New Insights in the Removal of the Hydantoins, Oxidation Product of Pyrimidines, via the Base Excision and Nucleotide Incision Repair Pathways. PLoS One 6(7):e21039
Gallego O, et al.  (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol Syst Biol 6():430
Bao G and Kow YW  (2009) Effect of sequence context and direction of replication on AP site bypass in Saccharomyces cerevisiae. Mutat Res 669(1-2):147-54
Ho CK, et al.  (2009) Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome. PLoS One 4(9):e6993
Daviet S, et al.  (2007) Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway. DNA Repair (Amst) 6(1):8-18
Starostin KV, et al.  (2007) [Interactions of pro- and eukaryotic DNA repair enzymes with oligodeoxyribonucleotides containing clustered lesions] Mol Biol (Mosk) 41(1):112-20
Bennett SE and Kitner J  (2006) Characterization of the aldehyde reactive probe reaction with AP-sites in DNA: influence of AP-lyase on adduct stability. Nucleosides Nucleotides Nucleic Acids 25(7):823-42
Seiple L, et al.  (2006) Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res 34(1):140-51
Ishchenko AA, et al.  (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90
Guzder SN, et al.  (2004) Requirement of yeast Rad1-Rad10 nuclease for the removal of 3'-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev 18(18):2283-91
Ishchenko AA, et al.  (2004) Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases. Biochemistry 43(48):15210-6
Ishchenko AA, et al.  (2003) Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases. Nucleic Acids Res 31(21):6344-53
Meadows KL, et al.  (2003) Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res 31(19):5560-7
Guillet M and Boiteux S  (2002) Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae. EMBO J 21(11):2833-41
Simon JA, et al.  (2000) Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60(2):328-33
Torres-Ramos CA, et al.  (2000) Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast. Mol Cell Biol 20(10):3522-8
Xiao W and Chow BL  (1998) Synergism between yeast nucleotide and base excision repair pathways in the protection against DNA methylation damage. Curr Genet 33(2):92-9
Xiao W, et al.  (1996) The repair of DNA methylation damage in Saccharomyces cerevisiae. Curr Genet 30(6):461-8
Johnson AW and Demple B  (1988) Yeast DNA 3'-repair diesterase is the major cellular apurinic/apyrimidinic endonuclease: substrate specificity and kinetics. J Biol Chem 263(34):18017-22