PDR5/YOR153W Literature Guide Help

Other names published for PDR5: LEM1, YDR1, STS1, ATP-binding cassette multidrug transporter PDR5, YOR153W

PDR5 LITERATURE TOPICS

PDR5 - Substrates/Ligands/Cofactors (38)

Results: 1 - 30 of 38 records
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ReferenceOther Genes Addressed
Guo X, et al.  (2012) A Mutation in Intracellular Loop 4 Affects the Drug-Efflux Activity of the Yeast Multidrug Resistance ABC Transporter Pdr5p. PLoS One 7(1):e29520
Schlecht U, et al.  (2012) Multiplex assay for condition-dependent changes in protein-protein interactions. Proc Natl Acad Sci U S A 109(23):9213-8
da Silva FR, et al.  (2011) Oroidin inhibits the activity of the multidrug resistance target pdr5p from yeast plasma membranes. J Nat Prod 74(2):279-82
Ananthaswamy N, et al.  (2010) The signaling interface of the yeast multidrug transporter pdr5 adopts a cis conformation, and there are functional overlap and equivalence of the deviant and canonical q-loop residues. Biochemistry 49(21):4440-9
Collins GA, et al.  (2010) Combined chemical and genetic approach to inhibit proteolysis by the proteasome. Yeast 27(11):965-74
Krasowska A, et al.  (2010) Cell ATP level of Saccharomyces cerevisiae sensitively responds to culture growth and drug-inflicted variations in membrane integrity and PDR pump activity. Biochem Biophys Res Commun 395(1):51-5
Hendrych T, et al.  (2009) Characterization of the kinetics and mechanisms of inhibition of drugs interacting with the S. cerevisiae multidrug resistance pumps Pdr5p and Snq2p. Biochim Biophys Acta 1788(3):717-23
Kolaczkowski M, et al.  (2009) New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters. Antimicrob Agents Chemother 53(4):1516-27
Ernst R, et al.  (2008) A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Proc Natl Acad Sci U S A 105(13):5069-74
Rutledge RM, et al.  (2008) Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux? Mol Genet Genomics 279(6):573-83
Sauna ZE, et al.  (2008) Mutations Define Cross-talk between the N-terminal Nucleotide-binding Domain and Transmembrane Helix-2 of the Yeast Multidrug Transporter Pdr5: POSSIBLE CONSERVATION OF A SIGNALING INTERFACE FOR COUPLING ATP HYDROLYSIS TO DRUG TRANSPORT. J Biol Chem 283(50):35010-22
Golin J, et al.  (2007) Complete Inhibition of the Pdr5p Multidrug Efflux Pump ATPase Activity by Its Transport Substrate Clotrimazole Suggests that GTP as Well as ATP May Be Used as an Energy Source. Biochemistry 46(45):13109-19
Hanson L, et al.  (2005) The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5p, a major yeast drug transporter. Biochemistry 44(28):9703-13
Hiraga K, et al.  (2005) Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae. Biochem Biophys Res Commun 328(4):1119-25
Tutulan-Cunita AC, et al.  (2005) Mutational analysis of the yeast multidrug resistance ABC transporter Pdr5p with altered drug specificity. Genes Cells 10(5):409-20
Yamamoto S, et al.  (2005) A new function of isonitrile as an inhibitor of the Pdr5p multidrug ABC transporter in Saccharomyces cerevisiae. Biochem Biophys Res Commun 330(2):622-8
Kaur R, et al.  (2004) Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. Antimicrob Agents Chemother 48(5):1600-13
Niimi K, et al.  (2004) Chemosensitization of fluconazole resistance in Saccharomyces cerevisiae and pathogenic fungi by a D-octapeptide derivative. Antimicrob Agents Chemother 48(4):1256-71
Conseil G, et al.  (2003) Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydrophobic estradiol-derivative RU49953. Biochim Biophys Acta 1614(2):131-4
Golin J, et al.  (2003) Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux. J Biol Chem 278(8):5963-9
Goossens A, et al.  (2003) Secretion of secondary metabolites by ATP-binding cassette transporters in plant cell suspension cultures. Plant Physiol 131(3):1161-4
Kolaczkowski M, et al.  (2003) Phenothiazines as potent modulators of yeast multidrug resistance. Int J Antimicrob Agents 22(3):279-83
Di Pietro A, et al.  (2002) Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell Mol Life Sci 59(2):307-22
Kurita S, et al.  (2002) Studies on the antimicrobial mechanisms of capsaicin using yeast DNA microarray. Biosci Biotechnol Biochem 66(3):532-6
Navarre C, et al.  (2002) Subproteomics: identification of plasma membrane proteins from the yeast Saccharomyces cerevisiae. Proteomics 2(12):1706-14
Teixeira MC and Sa-Correia I  (2002) Saccharomyces cerevisiae resistance to chlorinated phenoxyacetic acid herbicides involves Pdr1p-mediated transcriptional activation of TPO1 and PDR5 genes. Biochem Biophys Res Commun 292(2):530-7
Conseil G, et al.  (2001) Protein kinase C effectors bind to multidrug ABC transporters and inhibit their activity. Biochemistry 40(8):2564-71
Hiraga K, et al.  (2001) A novel screening for inhibitors of a pleiotropic drug resistant pump, Pdr5, in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 65(7):1589-95
Hu W, et al.  (2001) The ABC transporter Pdr5p mediates the efflux of nonsteroidal ecdysone agonists in Saccharomyces cerevisiae. Eur J Biochem 268(12):3416-22
Retnakaran A, et al.  (2001) Mode of action of the ecdysone agonist tebufenozide (RH-5992), and an exclusion mechanism to explain resistance to it. Pest Manag Sci 57(10):951-7
Results: 1 - 30 of 38 records
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