KEX2/YNL238W Literature Guide Help

Other names published for KEX2: QDS1, VMA45, SRB1, kexin, yscF, YNL238W

KEX2 - Substrates/Ligands/Cofactors (99)

Results: 1 - 30 of 99 records
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ReferenceOther Genes Addressed
Nakanishi A, et al.  (2012) Effect of pretreatment of hydrothermally processed rice straw with laccase-displaying yeast on ethanol fermentation. Appl Microbiol Biotechnol 94(4):939-48
Sato K, et al.  (2009) Kei1: a novel subunit of inositolphosphorylceramide synthase, essential for its enzyme activity and Golgi localization. Mol Biol Cell 20(20):4444-57
Bader O, et al.  (2008) Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol 8:116
Wheatley JL and Holyoak T  (2007) Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2. Proc Natl Acad Sci U S A 104(16):6626-31
Han HE, et al.  (2005) Engineering of Kex2 variants exhibiting altered substrate specificity. Biochem Biophys Res Commun 337(4):1102-6
Holyoak T, et al.  (2004) Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases. Biochemistry 43(9):2412-21
Ringe D, et al.  (2004) Protein structure to function: insights from computation. Cell Mol Life Sci 61(4):387-92
Rockwell NC and Thorner JW  (2004) The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing. Trends Biochem Sci 29(2):80-7
Holyoak T, et al.  (2003) 2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor. Biochemistry 42(22):6709-18
Komiyama T, et al.  (2003) Optimization of protease-inhibitor interactions by randomizing adventitious contacts. Proc Natl Acad Sci U S A 100(14):8205-10
Lee J, et al.  (2003) The influence of glycosylation on secretion, stability, and immunogenicity of recombinant HBV pre-S antigen synthesized in Saccharomyces cerevisiae. Biochem Biophys Res Commun 303(2):427-32
Kim SY, et al.  (2002) Detection of site-specific proteolysis in secretory pathways. Biochem Biophys Res Commun 296(2):419-24
Riffer F, et al.  (2002) Mutational analysis of K28 preprotoxin processing in the yeast Saccharomyces cerevisiae. Microbiology 148(Pt 5):1317-28
Lesage G, et al.  (2001) Mechanism of Kex2p inhibition by its proregion. FEBS Lett 508(3):332-6
Oda K, et al.  (2001) Cloning and rational mutagenesis of kexstatin I, a potent proteinaceous inhibitor of Kex2 proteinase. Biochem J 355(Pt 2):339-46
Rockwell NC and Fuller RS  (2001) Differential utilization of enzyme-substrate interactions for acylation but not deacylation during the catalytic cycle of Kex2 protease. J Biol Chem 276(42):38394-9
Rockwell NC and Fuller RS  (2001) Direct measurement of acylenzyme hydrolysis demonstrates rate-limiting deacylation in cleavage of physiological sequences by the processing protease Kex2. Biochemistry 40(12):3657-65
Hopkins BD, et al.  (2000) Introduction of Kex2 cleavage sites in fusion proteins for monitoring localization and transport in yeast secretory pathway. Methods Enzymol 327:107-18
Kjeldsen T  (2000) Yeast secretory expression of insulin precursors. Appl Microbiol Biotechnol 54(3):277-86
Komiyama T and Fuller RS  (2000) Engineered eglin c variants inhibit yeast and human proprotein processing proteases, Kex2 and furin. Biochemistry 39(49):15156-65
Lewis MJ, et al.  (2000) Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes. Mol Biol Cell 11(1):23-38
Moulard M and Decroly E  (2000) Maturation of HIV envelope glycoprotein precursors by cellular endoproteases. Biochim Biophys Acta 1469(3):121-32
Suzuki Y, et al.  (2000) Effect of amino acid substitution at the P(3) and P(4) subsites of fusion proteins on kex2 protease activity. Biotechnol Appl Biochem 32 ( Pt 1):53-60
Greenfield JP, et al.  (1999) Generation of the amyloid-beta peptide N terminus in Saccharomyces cerevisiae expressing human Alzheimer's amyloid-beta precursor protein. J Biol Chem 274(48):33843-6
Henkel MK, et al.  (1999) Endocytic delivery of intramolecularly quenched substrates and inhibitors to the intracellular yeast Kex2 protease1. Biochem J 341 ( Pt 2)():445-52
Moukadiri I, et al.  (1999) Identification of two mannoproteins released from cell walls of a Saccharomyces cerevisiae mnn1 mnn9 double mutant by reducing agents. J Bacteriol 181(16):4741-5
Bevan A, et al.  (1998) Quantitative assessment of enzyme specificity in vivo: P2 recognition by Kex2 protease defined in a genetic system. Proc Natl Acad Sci U S A 95(18):10384-9
Rockwell NC and Fuller RS  (1998) Interplay between S1 and S4 subsites in Kex2 protease: Kex2 exhibits dual specificity for the P4 side chain. Biochemistry 37(10):3386-91
Bessmertnaya LYa, et al.  (1997) Specific cleavage of hybrid proteins by proteinase encoded by the KEX2 gene. Biochemistry (Mosc) 62(8):850-7
Mrsa V, et al.  (1997) Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. Yeast 13(12):1145-54
Results: 1 - 30 of 99 records
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