FKS1/YLR342W Literature Guide Help

Other names published for FKS1: CND1, CWH53, ETG1, GSC1, PBR1, YLR342W

FKS1 - Substrates/Ligands/Cofactors (17)

ReferenceOther Genes Addressed
Walker SS, et al.  (2011) Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors. Antimicrob Agents Chemother 55(11):5099-106
Garcia-Effron G, et al.  (2008) A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility. Antimicrob Agents Chemother 52(7):2305-12
Park S, et al.  (2005) Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. Antimicrob Agents Chemother 49(8):3264-73
Ohyama T, et al.  (2004) FKS1 mutations responsible for selective resistance of Saccharomyces cerevisiae to the novel 1,3-beta-glucan synthase inhibitor arborcandin C. Antimicrob Agents Chemother 48(1):319-22
Kondoh O, et al.  (2002) Differential sensitivity between Fks1p and Fks2p against a novel beta -1,3-glucan synthase inhibitor, aerothricin3 [corrected]. J Biol Chem 277(44):41744-9
Bang KH, et al.  (2000) Inhibition of fungal cell wall synthesizing enzymes by trans-cinnamaldehyde. Biosci Biotechnol Biochem 64(5):1061-3
Onishi J, et al.  (2000) Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors. Antimicrob Agents Chemother 44(2):368-77
Takasuka T, et al.  (1995) Cell wall synthesis specific cytocidal effect of Hansenula mrakii toxin-1 on Saccharomyces cerevisiae. Cell Mol Biol Res 41(6):575-81
Ko YT, et al.  (1994) Inhibition of yeast (1,3)-beta-glucan synthase by phospholipase A2 and its reaction products. Biochim Biophys Acta 1193(1):31-40
Mol PC, et al.  (1994) A GTP-binding protein regulates the activity of (1-->3)-beta-glucan synthase, an enzyme directly involved in yeast cell wall morphogenesis. J Biol Chem 269(49):31267-74
Ruiz T and Rodriguez L  (1989) Effect of alpha factor pheromone on the activity of enzymes which catalyze the synthesis and hydrolysis of cell wall structural polymers from Saccharomyces cerevisiae. Biochem Int 19(3):571-81
Kang MS, et al.  (1986) The effect of papulacandin B on (1----3)-beta-D-glucan synthetases. A possible relationship between inhibition and enzyme conformation. Carbohydr Res 149(1):13-21
Guillen A, et al.  (1985) Endogenous factors that modulate yeast glucan synthetase in cell-free extracts. Biochim Biophys Acta 842(2-3):151-61
Yamaguchi H, et al.  (1985) Effect of aculeacin A, a wall-active antibiotic, on synthesis of the yeast cell wall. Microbiol Immunol 29(7):609-23
Leal F, et al.  (1984) An examination of factors affecting the instability of Saccharomyces cerevisiae glucan synthetase in cell free extracts. Arch Microbiol 137(3):209-14
Notario V, et al.  (1982) Interaction between yeast beta-(1 goes to 3)glucan synthetase and activating phosphorylated compounds. A kinetic study. J Biol Chem 257(4):1902-5
Sentandreu R, et al.  (1975) Synthesis of yeast wall glucan. J Gen Microbiol 90(1):13-20