SRS2/YJL092W Literature Guide Help

Other names published for SRS2: RADH, RADH1, HPR5, YJL092W

SRS2 - Substrates/Ligands/Cofactors (17)

ReferenceOther Genes Addressed
Anand RP, et al.  (2012) Overcoming natural replication barriers: differential helicase requirements. Nucleic Acids Res 40(3):1091-105
Marini V and Krejci L  (2012) Unwinding of synthetic replication and recombination substrates by Srs2. DNA Repair (Amst) 11(10):789-98
Zheng XF, et al.  (2011) Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein. DNA Repair (Amst) 10(10):1034-43
Manthey GM and Bailis AM  (2010) Rad51 Inhibits Translocation Formation by Non-Conservative Homologous Recombination in Saccharomyces cerevisiae. PLoS One 5(7):e11889
Prakash R, et al.  (2009) Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev 23(1):67-79
Dhar A and Lahue RS  (2008) Rapid unwinding of triplet repeat hairpins by Srs2 helicase of Saccharomyces cerevisiae. Nucleic Acids Res 36(10):3366-73
Dupaigne P, et al.  (2008) The Srs2 Helicase Activity Is Stimulated by Rad51 Filaments on dsDNA: Implications for Crossover Incidence during Mitotic Recombination. Mol Cell 29(2):243-54
Malik PS and Symington LS  (2008) Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2. Nucleic Acids Res 36(20):6504-10
Bhattacharyya S and Lahue RS  (2005) Srs2 helicase of Saccharomyces cerevisiae selectively unwinds triplet repeat DNA. J Biol Chem 280(39):33311-7
Papouli E, et al.  (2005) Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol Cell 19(1):123-33
Bhattacharyya S and Lahue RS  (2004) Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. Mol Cell Biol 24(17):7324-30
Krejci L, et al.  (2003) DNA helicase Srs2 disrupts the Rad51 presynaptic filament. Nature 423(6937):305-9
Van Komen S, et al.  (2003) ATPase and DNA helicase activities of the Saccharomyces cerevisiae anti-recombinase Srs2. J Biol Chem 278(45):44331-7
Vaze MB, et al.  (2002) Recovery from checkpoint-mediated arrest after repair of a double-strand break requires Srs2 helicase. Mol Cell 10(2):373-85
McVey M, et al.  (2001) The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics 157(4):1531-42
Paques F and Haber JE  (1997) Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol 17(11):6765-71
Rong L and Klein HL  (1993) Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae. J Biol Chem 268(2):1252-9