HXK2/YGL253W Literature Guide Help

Other names published for HXK2: HEX1, HKB, SCI2, hexokinase 2, YGL253W

HXK2 - Substrates/Ligands/Cofactors (81)

ReferenceOther Genes Addressed
Devaraneni PK, et al.  (2012) Polyol osmolytes stabilize native-like cooperative intermediate state of yeast hexokinase A at low pH. Biochimie 94(4):947-52
Dearmond PD, et al.  (2011) Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach. J Proteome Res 10(11):4948-58
Wang S, et al.  (2011) Switch between Life History Strategies Due to Changes in Glycolytic Enzyme Gene Dosage in Saccharomyces cerevisiae. Appl Environ Microbiol 77(2):452-9
Pelaez R, et al.  (2010) Functional domains of yeast hexokinase 2. Biochem J 432(1):181-90
Blume A, et al.  (2009) Specificity of ligand binding to yeast hexokinase PII studied by STD-NMR. Carbohydr Res 344(12):1567-74
Lorenz DR, et al.  (2009) A network biology approach to aging in yeast. Proc Natl Acad Sci U S A 106(4):1145-50
Stockbridge RB and Wolfenden R  (2009) The Intrinsic Reactivity of ATP and the Catalytic Proficiencies of Kinases Acting on Glucose, N-Acetylgalactosamine, and Homoserine: A THERMODYNAMIC ANALYSIS. J Biol Chem 284(34):22747-57
Wang T and Kang J  (2009) Hexokinase inhibitor screening based on adenosine 5'-diphosphate determination by electrophoretically mediated microanalysis. Electrophoresis 30(8):1349-54
Berthels NJ, et al.  (2008) Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains. Appl Microbiol Biotechnol 77(5):1083-91
Carvalho RS, et al.  (2008) Obtaining and selection of hexokinases-less strains of Saccharomyces cerevisiae for production of ethanol and fructose from sucrose. Appl Microbiol Biotechnol 77(5):1131-7
Kong DC, et al.  (2007) [Simulation and analysis of ethanol concentration response to enzyme amount changes in Saccharomyces cerevisiae glycolysis pathway model] Sheng Wu Gong Cheng Xue Bao 23(2):332-6
Mashego MR, et al.  (2005) Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats. FEMS Yeast Res 5(4-5):419-30
Romero CS, et al.  (2005) Structural and functional implications of the hexokinase-nickel interaction. J Inorg Biochem 99(12):2395-402
Bar D, et al.  (2003) The unique hexokinase of Kluyveromyces lactis. Molecular and functional characterization and evaluation of a role in glucose signaling. J Biol Chem 278(41):39280-6
Bianconi ML  (2003) Calorimetric determination of thermodynamic parameters of reaction reveals different enthalpic compensations of the yeast hexokinase isozymes. J Biol Chem 278(21):18709-13
Filfil R and Chalikian TV  (2003) Volumetric and spectroscopic characterizations of glucose-hexokinase association. FEBS Lett 554(3):351-6
Gao H and Leary JA  (2003) Multiplex inhibitor screening and kinetic constant determinations for yeast hexokinase using mass spectrometry based assays. J Am Soc Mass Spectrom 14(3):173-81
Horak J, et al.  (2002) Two distinct proteolytic systems responsible for glucose-induced degradation of fructose-1,6-bisphosphatase and the Gal2p transporter in the yeast Saccharomyces cerevisiae share the same protein components of the glucose signaling pathway. J Biol Chem 277(10):8248-54
Golbik R, et al.  (2001) Regulation of phosphotransferase activity of hexokinase 2 from Saccharomyces cerevisiae by modification at serine-14. Biochemistry 40(4):1083-90
Gonzalez B, et al.  (2000) Dynamic in vivo (31)P nuclear magnetic resonance study of Saccharomyces cerevisiae in glucose-limited chemostat culture during the aerobic-anaerobic shift. Yeast 16(6):483-97
Guerra R and Bianconi ML  (2000) Increased stability and catalytic efficiency of yeast hexokinase upon interaction with zwitterionic micelles. Kinetics and conformational studies. Biosci Rep 20(1):41-9
Teusink B, et al.  (2000) Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry. Eur J Biochem 267(17):5313-29
Alms GR, et al.  (1999) Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome. EMBO J 18(15):4157-68
Kraakman LS, et al.  (1999) Structure-function analysis of yeast hexokinase: structural requirements for triggering cAMP signalling and catabolite repression. Biochem J 343 Pt 1():159-68
Blazquez MA, et al.  (1993) Trehalose-6-phosphate, a new regulator of yeast glycolysis that inhibits hexokinases. FEBS Lett 329(1-2):51-4
Arora KK, et al.  (1990) Glucose phosphorylation. Interaction of a 50-amino acid peptide of yeast hexokinase with trinitrophenyl ATP. J Biol Chem 265(9):5324-8
Puri RN, et al.  (1988) Inactivation of yeast hexokinase by o-phthalaldehyde: evidence for the presence of a cysteine and a lysine at or near the active site. Biochim Biophys Acta 957(1):34-46
Ruan K and Weber G  (1988) Dissociation of yeast hexokinase by hydrostatic pressure. Biochemistry 27(9):3295-301
Tamura JK, et al.  (1988) The adenine nucleotide binding site on yeast hexokinase PII. Affinity labeling of Lys-111 by pyridoxal 5'-diphospho-5'-adenosine. J Biol Chem 263(16):7907-12
Woolfitt AR, et al.  (1988) Synergistic binding of glucose and aluminium ATP to hexokinase from Saccharomyces cerevisiae. Biochim Biophys Acta 955(3):346-51