RAD6/YGL058W Literature Guide Help

Other names published for RAD6: UBC2, PSO8, E2 ubiquitin-conjugating protein RAD6, YGL058W

RAD6 - Substrates/Ligands/Cofactors (23)

ReferenceOther Genes Addressed
Ha SW, et al.  (2012) The N-terminal domain of Rpn4 serves as a portable ubiquitin-independent degron and is recognized by specific 19S RP subunits. Biochem Biophys Res Commun 419(2):226-31
Hwang CS, et al.  (2010) The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nat Cell Biol 12(12):1177-85
Kim J and Roeder RG  (2009) Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast. J Biol Chem 284(31):20582-92
Lundh F, et al.  (2009) Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry 48(21):4497-505
Prakash S, et al.  (2009) Substrate selection by the proteasome during degradation of protein complexes. Nat Chem Biol 5(1):29-36
Ju D, et al.  (2008) Genome-wide analysis identifies MYND-domain protein Mub1 as an essential factor for Rpn4 ubiquitylation. Mol Cell Biol 28(4):1404-12
Moertl S, et al.  (2008) Regulation of double-stranded DNA gap repair by the RAD6 pathway. DNA Repair (Amst) 7(11):1893-906
Lee JS, et al.  (2007) Histone Crosstalk between H2B Monoubiquitination and H3 Methylation Mediated by COMPASS. Cell 131(6):1084-96
Kao CF, et al.  (2004) Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. Genes Dev 18(2):184-95
Hwang WW, et al.  (2003) A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. Mol Cell 11(1):261-6
Ng HH, et al.  (2003) The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B. J Biol Chem 278(36):33625-8
Stelter P and Ulrich HD  (2003) Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425(6954):188-91
Boeira JM, et al.  (2002) Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae. Mutat Res 500(1-2):39-48
Hoege C, et al.  (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419(6903):135-41
Sun ZW and Allis CD  (2002) Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418(6893):104-8
Turner SD, et al.  (2002) The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription. Mol Cell Biol 22(12):4011-9
Simon JA, et al.  (2000) Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res 60(2):328-33
Loidl G, et al.  (1999) Bivalency as a principle for proteasome inhibition. Proc Natl Acad Sci U S A 96(10):5418-22
Kornitzer D, et al.  (1994) Regulated degradation of the transcription factor Gcn4. EMBO J 13(24):6021-30
Haas AL, et al.  (1991) Ubiquitin conjugation by the yeast RAD6 and CDC34 gene products. Comparison to their putative rabbit homologs, E2(20K) AND E2(32K). J Biol Chem 266(8):5104-12
Jentsch S, et al.  (1987) The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329(6135):131-4
Hoekstra MF and Malone RE  (1986) Excision repair functions in Saccharomyces cerevisiae recognize and repair methylation of adenine by the Escherichia coli dam gene. Mol Cell Biol 6(10):3555-8
Swietlinska Z, et al.  (1976) Survival and liquid holding recovery in UV-sensitive strains of Saccharomyces cerevisiae after treatment with chemical mutagens and radiation. Acta Microbiol Pol 25(4):295-305