SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Substrates/Ligands/Cofactors (47)

Results: 1 - 30 of 47 records
   1  2 
ReferenceOther Genes Addressed
Bheda P, et al.  (2012) Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2. Proc Natl Acad Sci U S A 109(16):E916-25
Tung SY, et al.  (2012) Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose. Cell Mol Life Sci 69(4):641-50
Oppikofer M, et al.  (2011) A dual role of H4K16 acetylation in the establishment of yeast silent chromatin.LID - 10.1038/emboj.2011.170 [doi] EMBO J ()
Zhu X, et al.  (2011) Mediator influences telomeric silencing and cellular life span. Mol Cell Biol 31(12):2413-21
Ozaydin B and Rine J  (2010) Expanded Roles of the Origin Recognition Complex in the Architecture and Function of Silenced Chromatin in Saccharomyces cerevisiae. Mol Cell Biol 30(3):626-39
Sanders BD, et al.  (2010) Structural basis for sirtuin function: What we know and what we don't. Biochim Biophys Acta 1804(8):1604-1616
Zhou BO, et al.  (2010) SWR1 complex poises heterochromatin boundaries for antisilencing activity propagation. Mol Cell Biol 30(10):2391-400
Biswas M, et al.  (2009) Limiting the extent of the RDN1 heterochromatin domain by a silencing barrier and Sir2 protein levels in Saccharomyces cerevisiae. Mol Cell Biol 29(10):2889-98
Dang W, et al.  (2009) Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459(7248):802-7
Du J, et al.  (2009) Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD. Biochemistry 48(13):2878-90
Johnson A, et al.  (2009) Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell 35(6):769-81
Lin YY, et al.  (2009) Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell 136(6):1073-84
Sanders BD, et al.  (2009) Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorg Med Chem 17(19):7031-41
Chou CC, et al.  (2008) Bypassing Sir2 and O-acetyl-ADP-ribose in transcriptional silencing. Mol Cell 31(5):650-9
McClure JM, et al.  (2008) Pnc1p-Mediated Nicotinamide Clearance Modifies the Epigenetic Properties of rDNA Silencing in Saccharomyces cerevisiae. Genetics 180(2):797-810
Wang CL, et al.  (2008) A yeast sir2 mutant temperature sensitive for silencing. Genetics 180(4):1955-62
Mead J, et al.  (2007) Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases. Mol Cell Biol 27(7):2466-75
Reverter-Branchat G, et al.  (2007) Chronological and replicative life-span extension in Saccharomyces cerevisiae by increased dosage of alcohol dehydrogenase 1. Microbiology 153(Pt 11):3667-3676
Thaminy S, et al.  (2007) Hst3 Is Regulated by Mec1-dependent Proteolysis and Controls the S Phase Checkpoint and Sister Chromatid Cohesion by Deacetylating Histone H3 at Lysine 56. J Biol Chem 282(52):37805-14
Chiani F, et al.  (2006) SIR2 modifies histone H4-K16 acetylation and affects superhelicity in the ARS region of plasmid chromatin in Saccharomyces cerevisiae. Nucleic Acids Res 34(19):5426-37
Vaquero A, et al.  (2006) SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 20(10):1256-61
Borra MT, et al.  (2005) Mechanism of human SIRT1 activation by resveratrol. J Biol Chem 280(17):17187-95
Khan AN and Lewis PN  (2005) Unstructured Conformations Are a Substrate Requirement for the Sir2 Family of NAD-dependent Protein Deacetylases. J Biol Chem 280(43):36073-8
Olaharski AJ, et al.  (2005) The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS Genet 1(6):e77
Sauve AA, et al.  (2005) Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition. Mol Cell 17(4):595-601
Borra MT, et al.  (2004) Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases. Biochemistry 43(30):9877-87
Couzin J  (2004) Scientific community. Aging research's family feud. Science 303(5662):1276-9
Lin SJ, et al.  (2004) Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev 18(1):12-6
Sauve AA and Schramm VL  (2004) SIR2: the biochemical mechanism of NAD(+)-dependent protein deacetylation and ADP-ribosyl enzyme intermediates. Curr Med Chem 11(7):807-26
Schmidt MT, et al.  (2004) Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation. J Biol Chem 279(38):40122-9
Results: 1 - 30 of 47 records
   1  2