RAD27/YKL113C Literature Guide Help

Other names published for RAD27: ERC11, RTH1, FEN1, YKL113C

RAD27 - Substrates/Ligands/Cofactors (22)

ReferenceOther Genes Addressed
Kantartzis A, et al.  (2012) Msh2-msh3 interferes with okazaki fragment processing to promote trinucleotide repeat expansions. Cell Rep 2(2):216-22
Pike JE, et al.  (2010) An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase. J Biol Chem 285(53):41712-23
Ho CK, et al.  (2009) Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome. PLoS One 4(9):e6993
Pike JE, et al.  (2009) Pif1 Helicase Lengthens Some Okazaki Fragment Flaps Necessitating Dna2 Nuclease/Helicase Action in the Two-nuclease Processing Pathway. J Biol Chem 284(37):25170-80
Stewart JA, et al.  (2009) Significance of the Dissociation of Dna2 by Flap Endonuclease 1 to Okazaki Fragment Processing in Saccharomyces cerevisiae. J Biol Chem 284(13):8283-91
Sommer D, et al.  (2008) Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae. Nucleic Acids Res 36(14):4699-707
Singh P, et al.  (2007) Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments. J Biol Chem 282(6):3465-77
Rossi ML and Bambara RA  (2006) Reconstituted Okazaki fragment processing indicates two pathways of primer removal. J Biol Chem 281(36):26051-61
Seiple L, et al.  (2006) Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res 34(1):140-51
Stone JE and Petes TD  (2006) Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 173(3):1223-39
Kao HI, et al.  (2004) On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing. J Biol Chem 279(15):15014-24
Tseng HM and Tomkinson AE  (2004) Processing and joining of DNA ends coordinated by interactions among Dnl4/Lif1, Pol4, and FEN-1. J Biol Chem 279(46):47580-8
Bae KH, et al.  (2003) Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro. Nucleic Acids Res 31(12):3006-15
Kao HI, et al.  (2002) Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. J Biol Chem 277(17):14379-89
Lewis LK, et al.  (2002) Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160(1):49-62
Rydberg B and Game J  (2002) Excision of misincorporated ribonucleotides in DNA by RNase H (type 2) and FEN-1 in cell-free extracts. Proc Natl Acad Sci U S A 99(26):16654-9
Moreau S, et al.  (2001) Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics 159(4):1423-33
Xie Y, et al.  (2001) Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage. Mol Cell Biol 21(15):4889-99
Alleva JL and Doetsch PW  (2000) The nature of the 5'-terminus is a major determinant for DNA processing by Schizosaccharomyces pombe Rad2p, a FEN-1 family nuclease. Nucleic Acids Res 28(15):2893-901
Qiu J, et al.  (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
Biswas EE, et al.  (1997) Stimulation of RTH1 nuclease of the yeast Saccharomyces cerevisiae by replication protein A. Biochemistry 36(20):5955-62
Zhu FX, et al.  (1997) Purification and characterization of the DNA polymerase alpha associated exonuclease: the RTH1 gene product. Biochemistry 36(20):5947-54