ERG9/YHR190W Literature Guide Help

Other names published for ERG9: bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase, YHR190W

ERG9 - Substrates/Ligands/Cofactors (12)

ReferenceOther Genes Addressed
Madsen KM, et al.  (2011) Linking Genotype and Phenotype of Saccharomyces cerevisiae Strains Reveals Metabolic Engineering Targets and Leads to Triterpene Hyper-Producers. PLoS One 6(3):e14763
Li X, et al.  (2010) Extensive in vivo metabolite-protein interactions revealed by large-scale systematic analyses. Cell 143(4):639-50
Pan JJ, et al.  (2009) Recombinant squalene synthase. synthesis of cyclopentyl non-head-to-tail triterpenes. J Org Chem 74(19):7562-5
Daicho K, et al.  (2007) The ergosterol biosynthesis inhibitor zaragozic acid promotes vacuolar degradation of the tryptophan permease Tat2p in yeast. Biochim Biophys Acta 1768(7):1681-1690
Radisky ES and Poulter CD  (2000) Squalene synthase: steady-state, pre-steady-state, and isotope-trapping studies. Biochemistry 39(7):1748-60
Kalinowski SS and Mookhtiar KA  (1999) Mechanism of inhibition of yeast squalene synthase by substrate analog inhibitors. Arch Biochem Biophys 368(2):338-46
Mookhtiar KA, et al.  (1994) Yeast squalene synthase. A mechanism for addition of substrates and activation by NADPH. J Biol Chem 269(15):11201-7
Hata S, et al.  (1982) Effect of detergents on sterol synthesis in a cell-free system of yeast. J Lipid Res 23(6):803-10
Agnew WS and Popjak G  (1978) Squalene synthetase. Stoichiometry and kinetics of presqualene pyrophosphate and squalene synthesis by yeast microsomes. J Biol Chem 253(13):4566-73
Ortiz de Montellano PR, et al.  (1977) Substrate selectivity of squalene synthetase. Biochemistry 16(12):2680-5
Beytia E, et al.  (1973) Squalene synthetase. 3. Mechanism of the reaction. J Biol Chem 248(5):1856-67
Qureshi AA, et al.  (1973) Squalene synthetase. II. Purification and properties of bakers' yeast enzyme. J Biol Chem 248(5):1848-55